| Company Name: |
Nextpeptide Inc |
| Tel: |
+86-0571-81612335 +8613336028439 |
| Email: |
sales@nextpeptide.com |
|
| | 1,1,1-Trifluoroethyl-PEG4-Aminooxy Basic information |
| Product Name: | 1,1,1-Trifluoroethyl-PEG4-Aminooxy | | Synonyms: | 1,1,1-Trifluoroethyl-PEG4-Aminooxy;Hydroxylamine, O-(14,14,14-trifluoro-3,6,9,12-tetraoxatetradec-1-yl)-;O-(14,14,14-Trifluoro-3,6,9,12-tetraoxatetradecyl)hydroxylamine | | CAS: | 1895922-78-7 | | MF: | C10H20F3NO5 | | MW: | 291.26 | | EINECS: | | | Product Categories: | | | Mol File: | 1895922-78-7.mol |  |
| | 1,1,1-Trifluoroethyl-PEG4-Aminooxy Chemical Properties |
| Boiling point | 348.3±42.0 °C(Predicted) | | density | 1.186±0.06 g/cm3(Predicted) | | pka | 4.21±0.70(Predicted) |
| | 1,1,1-Trifluoroethyl-PEG4-Aminooxy Usage And Synthesis |
| Description | 1,1,1-Trifluoroethyl-PEG4-aminooxy is a fluorine containing PEG molecule. The aminooxy group can be used in bioconjugation and It reacts with an aldehyde to form an oxime bond. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended. | | Uses | 1,1,1-Trifluoroethyl-PEG4-aminooxy is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | 1,1,1-Trifluoroethyl-PEG4-Aminooxy Preparation Products And Raw materials |
|