t-Boc-N-Amido-PEG2-Ms manufacturers
- Boc-N-PEG2-Ms
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2026-07-16
- CAS:302331-20-0
- Purity:
- Supply Ability: 10g
- Boc-N-PEG2-Ms
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2025-08-22
- CAS:302331-20-0
- Purity:
- Supply Ability: 10g
- Boc-NH-PEG2-Ms
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2025-06-07
- CAS:302331-20-0
- Min. Order: 5g
- Purity: >98.00%
- Supply Ability: 5g
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| | t-Boc-N-Amido-PEG2-Ms Basic information |
| Product Name: | t-Boc-N-Amido-PEG2-Ms | | Synonyms: | t-Boc-N-Amido-PEG2-Ms;Boc-N-PEG2-Ms;Boc-NH-PEG2-Ms;Boc-N-PEG2-Oms;5,8-Dioxa-9-thia-2-azadecanoic acid, 1,1-dimethylethyl ester, 9,9-dioxide;2-(2-((tert-Butoxycarbonyl)amino)ethoxy)ethyl methanesulfonate;BocNH-PEG2-OMs | | CAS: | 302331-20-0 | | MF: | C10H21NO6S | | MW: | 283.34 | | EINECS: | | | Product Categories: | | | Mol File: | 302331-20-0.mol |  |
| | t-Boc-N-Amido-PEG2-Ms Chemical Properties |
| Boiling point | 439.8±30.0 °C(Predicted) | | density | 1.182±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, protect from light | | form | Liquid | | pka | 12.18±0.46(Predicted) | | color | Colorless to light yellow |
| | t-Boc-N-Amido-PEG2-Ms Usage And Synthesis |
| Description | t-Boc-N-Amido-PEG2-Ms is a PEG linker that contains a Boc protecting group and a mesyl group. The t-Boc group can be removed under acidic conditions. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases the water solubility of the compound. Longer PEG chains increase the water solubility properties of the compound. | | Uses | Boc-N-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | t-Boc-N-Amido-PEG2-Ms Preparation Products And Raw materials |
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