Bis-aminooxy-PEG4 manufacturers
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| | Bis-aminooxy-PEG4 Basic information |
| Product Name: | Bis-aminooxy-PEG4 | | Synonyms: | Bis-aminooxy-PEG4;~{O}-[2-[2-[2-[2-(2-aminooxyethoxy)ethoxy]ethoxy]ethoxy]ethyl]hydroxylamine;Aminooxy-PEG4-Aminooxy;Hydroxylamine, O,O'-(3,6,9,12-tetraoxatetradecane-1,14-diyl)bis-;O-[14-(aminooxy)-3,6,9,12-tetraoxatetradecan-1-yl]hydroxylamine;O,O'-(3,6,9,12-Tetraoxatetradecane-1,14-diyl)bis(hydroxylamine) | | CAS: | 98627-72-6 | | MF: | C10H24N2O6 | | MW: | 268.31 | | EINECS: | | | Product Categories: | | | Mol File: | 98627-72-6.mol |  |
| | Bis-aminooxy-PEG4 Chemical Properties |
| storage temp. | 2-8°C, sealed storage, away from moisture and light | | solubility | Soluble in Water, DMSO, DCM, DMF | | form | Liquid | | color | Light yellow to yellow |
| | Bis-aminooxy-PEG4 Usage And Synthesis |
| Description | Bis-aminooxy-PEG4 is a homobifunctional crosslinking reagent with great water soolubility. Aminooxy (ONH2) group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond or a hydroxylamine linkage under reduction condition Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended. | | Uses | Bis-aminooxy-PEG4 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bis-aminooxy-PEG4 Preparation Products And Raw materials |
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