Bis-aminooxy-PEG7 manufacturers
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| | Bis-aminooxy-PEG7 Basic information |
| Product Name: | Bis-aminooxy-PEG7 | | Synonyms: | Bis-aminooxy-PEG7;Hydroxylamine, O-[23-(aminooxy)-3,6,9,12,15,18,21-heptaoxatricos-1-yl]-;O-[23-(aminooxy)-3,6,9,12,15,18,21-heptaoxatricosan-1-yl]hydroxylamine | | CAS: | 1383980-52-6 | | MF: | C16H36N2O9 | | MW: | 400.46 | | EINECS: | | | Product Categories: | | | Mol File: | 1383980-52-6.mol |  |
| | Bis-aminooxy-PEG7 Chemical Properties |
| solubility | Soluble in Water, DMSO, DMF |
| | Bis-aminooxy-PEG7 Usage And Synthesis |
| Description | Bis-aminooxy-PEG7 molecule contains two aminooxy groups. The hydrophilic PEG spacer increases solubility in aqueous media. Aminooxy (ONH2) group is reactive with an aldehyde to form an oxime bond or a hydroxylamine linkage under reduction condition Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended. | | Uses | Bis-aminooxy-PEG7 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bis-aminooxy-PEG7 Preparation Products And Raw materials |
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