SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE manufacturers
|
| | SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE Basic information |
| | SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE Chemical Properties |
| density | 1.47±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | form | White to off-white solid | | pka | 3.56±0.10(Predicted) | | color | White to off-white | | biological source | rabbit | | Water Solubility | Soluble to 0.90 mg/ml in sterile water | | InChIKey | OXHYRVSBKWIFES-UHFFFAOYSA-N |
| Hazard Codes | T | | Risk Statements | 61 | | Safety Statements | 53-45 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE Usage And Synthesis |
| Uses | TRAP-14 (SFLLRNPNDKYEPF) is a synthetic thrombin receptor agonist peptide. | | Biological Activity | Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe has contractile effects on vascular and gastric smooth muscle. It stimulates the hydrolysis of phosphoinositides.', 'Thrombin receptor activator | | storage | Store at -20°C | | References | [1] Sugama Y, et al. Thrombin receptor 14-amino acid peptide mediates endothelial hyperadhesivity and neutrophil adhesion by P-selectin-dependent mechanism. Circ Res. 1992 Oct;71(4):1015-9. DOI:10.1161/01.res.71.4.1015
[2] Sabo T, et al. Structure-activity studies of the thrombin receptor activating peptide. Biochem Biophys Res Commun. 1992 Oct 30;188(2):604-10. DOI:10.1016/0006-291x(92)91099-c
[3] Maruyama Y, et al. Thrombin receptor agonist peptide decreases thrombomodulin activity in cultured human umbilical vein endothelial cells. Biochem Biophys Res Commun. 1994 Mar 30;199(3):1262-9. DOI:10.1006/bbrc.1994.1367 |
| | SER-PHE-LEU-LEU-ARG-ASN-PRO-ASN-ASP-LYS-TYR-GLU-PRO-PHE Preparation Products And Raw materials |
|