- 1-Pyrenylboronic acid
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- $30.00
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2022-09-23
- CAS:164461-18-1
- Min. Order: 1Kg
- Purity: 99.0% up
- Supply Ability: 20 tons per month
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| | 1-Pyrenylboronic acid Basic information |
| Product Name: | 1-Pyrenylboronic acid | | Synonyms: | Boronic acid, B-1-pyrenyl-;Pyrene-1-boronic acid 97%;B-1-Pyrenylboronic acid;1-Pyreneboronic Acid (contains varying amounts of Anhydride);1-Pyreneboronic acid, 1-Pyrenylboronic acid;1-Pyrenylboronic aci;1-Pyrenyboronic acid;1-Boronopyrene | | CAS: | 164461-18-1 | | MF: | C16H11BO2 | | MW: | 246.07 | | EINECS: | 813-398-3 | | Product Categories: | OLED materials,pharm chemical,electronic;Aryl Boronic Acids;Boronic Acids and Derivatives;Chemical Synthesis;Organometallic Reagents;Unsubstituted Aryl Boronic Acids;fine chemicals, specialty chemicals, intermediates, electronic chemical, organic synthesis;fine chemicals, specialty chemicals, intermediates, electronic chemical, organic synthesis, functional materials;Boron Compounds;blocks;BoronicAcids;Electronic Chemicals;B (Classes of Boron Compounds);Boronic Acids;Pyrenes;OLED | | Mol File: | 164461-18-1.mol |  |
| | 1-Pyrenylboronic acid Chemical Properties |
| Melting point | 247-251 °C(lit.) | | Boiling point | 509.4±33.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | pka | 8.53±0.30(Predicted) | | form | Powder | | color | Pale yellow | | Water Solubility | Slightly soluble in water. | | InChI | InChI=1S/C16H11BO2/c18-17(19)14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9,18-19H | | InChIKey | MWEKPLLMFXIZOC-UHFFFAOYSA-N | | SMILES | B(C1=C2C3=C4C(C=C2)=CC=CC4=CC=C3C=C1)(O)O | | CAS DataBase Reference | 164461-18-1(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29319090 | | Storage Class | 11 - Combustible Solids |
| | 1-Pyrenylboronic acid Usage And Synthesis |
| Chemical Properties | White to light brown solid | | Uses | It is an important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field. Also used as a intermediate for organic light-emitting diode(OLED). | | Uses | suzuki reaction | | Synthesis | The general procedure for the synthesis of 1-pyrenylboronic acid from trimethyl borate and 1-bromopyrene was as follows: 1-bromopyrene (30 g, 107 mmol) was added to a round-bottom flask and dissolved in 240 mL of tetrahydrofuran (THF). Under cooling conditions, n-BuLi (1.6 M, 80 mL) in hexane was slowly added dropwise, keeping the reaction temperature at -78 °C. After the dropwise addition was completed, the reaction mixture continued to be stirred at -78 °C for about 1 hour. Subsequently, trimethyl borate (15.5 g, 149 mmol) was added and stirring was continued at -78 °C for 1 hour. After that, the reaction mixture was warmed up to room temperature and stirred for about 2 hours. After completion of the reaction, the reaction solution was adjusted to acidic with 2N HCl. Extraction was carried out with ethyl acetate (EA) and hexane, and the organic phases were combined and concentrated under reduced pressure to remove the solvent to give 19.5 g of 1-pyrenylboronic acid in 74% yield. | | References | [1] Patent: KR101515814, 2015, B1. Location in patent: Paragraph 0343; 0344
[2] Patent: KR101503771, 2015, B1. Location in patent: Paragraph 0215; 0216
[3] Patent: US2014/131664, 2014, A1. Location in patent: Paragraph 0025-0026
[4] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1998, # 7, p. 1263 - 1268
[5] ChemPlusChem, 2013, vol. 78, # 10, p. 1288 - 1295 |
| | 1-Pyrenylboronic acid Preparation Products And Raw materials |
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