Biotin-PEG4-Amide-C6-Azide manufacturers
|
| | Biotin-PEG4-Amide-C6-Azide Basic information |
| Product Name: | Biotin-PEG4-Amide-C6-Azide | | Synonyms: | Biotin-PEG4-Amide-C6-Azide;Biotin-PEG4-Amine-C6-Azide;Biotin-PEG-4-Amide-C6-Azide,Biotin PEG4 Amide C6 Azide,Inhibitor,BiotinPEG4AmideC6Azide,PROTAC Linkers,inhibit;Biotin-PEG4-Amide-C6-Azide, 10 mM in DMSO;Biotin-PEG4-NH2-C6-N3 | | CAS: | 1006592-62-6 | | MF: | C27H49N7O7S | | MW: | 615.79 | | EINECS: | | | Product Categories: | | | Mol File: | 1006592-62-6.mol |  |
| | Biotin-PEG4-Amide-C6-Azide Chemical Properties |
| storage temp. | -20°C, sealed storage, away from moisture and light | | solubility | Soluble in DMSO, DCM, DMF | | form | Solid | | color | White to light yellow |
| | Biotin-PEG4-Amide-C6-Azide Usage And Synthesis |
| Description | Biotin Azide is a biotin compound that can react with terminal alkynes via a copper-catalyzed click reaction to produce a stable triazole linkage. | | Uses | Biotin-PEG4-Amide-C6-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-Amide-C6-Azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Biotin-PEG4-Amide-C6-Azide Preparation Products And Raw materials |
|