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| | D-ILE-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE Basic information |
| Product Name: | D-ILE-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE | | Synonyms: | S2288;D-Ile-Pro-Arg p-nitroanilide;D-ILE-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE;(2S)-1-[(2R,3R)-2-amino-3-methylpentanoyl]-N-[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide;S-2288(2HCl);D-Ile-Pro-Arg p-nitroanilide dihydrochloride;D-Ile-Pro-Arg-pNA·2HCl;H-D-Ile-Pro-Arg-pNA Dihydrochloride | | CAS: | 96323-41-0 | | MF: | C23H37ClN8O5 | | MW: | 541.05 | | EINECS: | | | Product Categories: | Activity;Chromogenic;Enzyme Substrates | | Mol File: | 96323-41-0.mol |  |
| | D-ILE-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE Chemical Properties |
| solubility | water: 1 mg/mL, clear, colorless to faintly yellow | | form | powder | | color | White to off-white | | Water Solubility | water: 1mg/mL, clear, colorless to faintly yellow | | InChIKey | YSYQQKNJMACZCI-ASLVLMPBNA-N | | SMILES | C([C@@H]1CCCN1C(=O)[C@H](N)[C@H](C)CC)(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1C=CC(N(=O)=O)=CC=1.Cl |&1:1,8,10,16,r| |
| Hazard Codes | Xn | | Risk Statements | 20/21/22-33-36/37/38-63 | | Safety Statements | 28-36/37-45 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 2
STOT SE 3 |
| | D-ILE-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE Usage And Synthesis |
| Uses | D-Ile-Pro-Arg p-nitroanilide dihydrochloride is a chromogenic peptide substrate of tissue plasminogen activator (tPA)[1]. | | References | [1] Chmielewska J, et al. Kinetics of the inhibition of plasminogen activators by the plasminogen-activator inhibitor. Evidence for 'second-site' interactions. Biochem J. 1988 Apr 15;251(2):327-32. DOI:10.1042/bj2510327 |
| | D-ILE-PRO-ARG P-NITROANILIDE DIHYDROCHLORIDE Preparation Products And Raw materials |
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