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2-Fluorocinnamic acid

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Company Name: Hebei Chuanghai Biotechnology Co., Ltd
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CAS:451-69-4
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Products Intro: Product Name:2-Fluorocinnamic acid
CAS:451-69-4
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CAS:451-69-4
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CAS:451-69-4
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Products Intro: Product Name:3-(2-Fluorophenyl)acrylic acid
CAS:451-69-4
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2-Fluorocinnamic acid manufacturers

  • 2-Fluorocinnamic acid
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  • $10.00 / 1KG
  • 2026-01-05
  • CAS:451-69-4
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt
  • 2-Fluorocinnamic acid
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  • $35.00 / 1kg
  • 2025-09-25
  • CAS:451-69-4
  • Min. Order: 1kg
  • Purity: 99%
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2-Fluorocinnamic acid Basic information
Product Name:2-Fluorocinnamic acid
Synonyms:-(2-Fluoro-phenyl)-acrylic acid;3-(2-fluorophenyl)-2-propenoicaci;3-(2-Fluorophenyl)propenoic acid;2-Fluorociamic acid;2-Fluorocinnamic acid, predominantly trans;(E)-3-(2-fluorophenyl)acrylic acid;3-(2-Fluorophenyl)prop-2-enoic acid, 3-(2-Fluorophenyl)acrylic acid;(E)-3-(2-fluorophenyl)-2-propenoate
CAS:451-69-4
MF:C9H7FO2
MW:166.15
EINECS:207-195-3
Product Categories:Cinnamic acid;Miscellaneous;Acids & Esters;Fluorine Compounds;C9;Carbonyl Compounds;Carboxylic Acids;Aromatic Cinnamic Acids, Esters and Derivatives;Fluoro-contained cinnamic acid series;451-69-4
Mol File:451-69-4.mol
2-Fluorocinnamic acid Structure
2-Fluorocinnamic acid Chemical Properties
Melting point 178-180 °C(lit.)
Boiling point 290°C (rough estimate)
density 1.2247 (estimate)
storage temp. Inert atmosphere,Room Temperature
pka4.31±0.10(Predicted)
form Crystalline Powder of Flakes
color White
BRN 1863963
InChIInChI=1S/C9H7FO2/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6H,(H,11,12)
InChIKeyIOUDZAFBPDDAMK-AATRIKPKSA-N
SMILESC(O)(=O)C=CC1=CC=CC=C1F
CAS DataBase Reference451-69-4(CAS DataBase Reference)
NIST Chemistry Reference2-Propenoic acid, 3-(2-fluorophenyl)-(451-69-4)
EPA Substance Registry System2-Propenoic acid, 3-(2-fluorophenyl)- (451-69-4)
Safety Information
Hazard Codes Xi,C
Risk Statements 36/37/38-34
Safety Statements 37/39-26-45-36/37/39-27-24/25
WGK Germany 3
RTECS GD9081000
HazardClass IRRITANT
HS Code 29163990
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
2-Fluorocinnamic acid English
SigmaAldrich English
ACROS English
ALFA English
2-Fluorocinnamic acid Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses2-Fluorocinnamic acid was used in the synthesis of acrylamide.
Synthesis

There are various methods for synthesizing o-fluorocinnamic acid, such as Perkin's method, Knoevenagel's method, o-fluorobenzaldehyde-acetone method, o-fluorobenzaldehyde-vinyl ketone method, o-fluorobenzaldehyde-acetic acid method, styrene-carbon tetrachloride method, Styrene-carbon monoxide method, styrene-carbon dioxide method, phenylchloromethane-anhydrous sodium acetate method, halogenated benzene-acrylic acid method, cinnamaldehyde oxidation method and so on. Most of the above methods have no practical industrial application value or have been eliminated due to high energy consumption, heavy pollution, high cost and low yield. At present, the main methods for the industrial production of o-fluorocinnamic acid are Perkin's method and styrene-carbon tetrachloride method. The author reviews and evaluates the progress of the synthesis of o-fluorocinnamic acid based on the classification of reaction materials.

2-Fluorocinnamic acid Preparation Products And Raw materials
Preparation Products2-FLUORO-DL-PHENYLALANINE-->2-FLUORO-D-PHENYLALANINE-->4-Fluoro-1-indanone-->(E)-3-(2-FLUORO-PHENYL)-ACRYLOYL CHLORIDE
Tag:2-Fluorocinnamic acid(451-69-4) Related Product Information
N-BUTYL CINNAMATE Cinnamic acid alpha-Methylcinnamic acid trans-Cinnamic acid Methyl cinnamate 4-Hydroxycinnamic acid 2-Nitrocinnamic acid Ethyl cinnamate Citric acid Ascoric Acid 4-Fluorocinnamic acid 2-BROMO-5-FLUOROCINNAMIC ACID,2-BROMO-5-FLUOROCINNAMIC ACID 3-CHLORO-4-FLUOROCINNAMIC ACID,3-CHLORO-4-FLUOROCINNAMIC ACID 2,3,4,5,6-PENTAFLUOROCINNAMIC ACID 3,5-DIFLUOROCINNAMIC ACID 2,3,5-TRIFLUOROCINNAMIC ACID 3-Fluorocinnamicacid 3,4,5-TRIFLUOROCINNAMIC ACID

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