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| | 3-Fluorocinnamicacid Basic information |
| | 3-Fluorocinnamicacid Chemical Properties |
| Melting point | 43-47 °C(lit.) | | Boiling point | 125 °C10.5 mm Hg(lit.) | | density | 0.892 | | Fp | 230 °F | | storage temp. | Inert atmosphere,Room Temperature | | form | powder to crystal | | pka | 4.29±0.10(Predicted) | | color | White to Almost white | | InChIKey | RTSIUKMGSDOSTI-SNAWJCMRSA-N | | CAS DataBase Reference | 458-46-8(CAS DataBase Reference) |
| | 3-Fluorocinnamicacid Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | (E)-3-(3-Fluorophenyl)acrylic Acid exhibits antineoplastic properties against breast cancer cells. A useful research chemical. | | Synthesis | 31g of m-fluorobenzaldehyde, 3.3g of pyridine was added to a four-necked flask, heated to 90 C with stirring, stirring in 5 batches to add 31.25g of malonic acid until it was completely dissolved, and after the addition of malonic acid, the temperature was raised to 110 C with stirring and refluxing for 90 min. 75mL of 10% hydrochloric acid was added to the four-necked flask, and the flask was cooled down to room temperature. Filter, wash the solid with hot water above 70 , until the pH of the wash solution was neutral and the wash solution was colorless. The solid was dried to obtain white flaky crystals with a yield of 79.5%. |
| | 3-Fluorocinnamicacid Preparation Products And Raw materials |
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