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- 5-Bromofuroic acid
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-
2026-06-30
- CAS:585-70-6
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 1000kg
- 5-Bromofuroic acid
-
- $1.00
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2019-07-12
- CAS:585-70-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 1ton
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| | 5-Bromofuroic acid Basic information |
| Product Name: | 5-Bromofuroic acid | | Synonyms: | 2-Furancarboxylic acid, 5-bromo-;2-Furoic acid, 5-bromo-;RARECHEM AL BE 0601;OTAVA-BB BB0125160212;5-BROMO-FURAN-2-CARBOXYLIC ACID;5-BROMOFUROIC ACID;5-BROMOPYROMUCIC ACID;AKOS AUF0674 | | CAS: | 585-70-6 | | MF: | C5H3BrO3 | | MW: | 190.98 | | EINECS: | 209-559-7 | | Product Categories: | API intermediates;Furans | | Mol File: | 585-70-6.mol |  |
| | 5-Bromofuroic acid Chemical Properties |
| Melting point | 188-190 °C(lit.) | | Boiling point | 281.6±25.0 °C(Predicted) | | density | 1.7703 (rough estimate) | | refractive index | 1.4690 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | pka | 2.84±0.10(Predicted) | | form | Crystalline Flakes or Powder | | color | White to cream or beige | | BRN | 118354 | | InChI | 1S/C5H3BrO3/c6-4-2-1-3(9-4)5(7)8/h1-2H,(H,7,8) | | InChIKey | YVTQHZDUDUCGRD-UHFFFAOYSA-N | | SMILES | OC(=O)c1ccc(Br)o1 | | CAS DataBase Reference | 585-70-6(CAS DataBase Reference) | | NIST Chemistry Reference | 5-Bromofuroic acid(585-70-6) |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 24/25-39-26 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29321900 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2 |
| | 5-Bromofuroic acid Usage And Synthesis |
| Chemical Properties | white to cream or beige crystalline flakes | | Uses | 5-Bromofuroic acid serves as a precursor for synthesizing 4-(methoxycarbonyl)phenyl 5-bromofuran-2-carboxylate via Steglich esterification with methylparaben, using DCC and DMAP[6]. | | Synthesis | Furan-2-carboxylic acid (2.50 g, 22.3 mmol) was used as starting material and dissolved in a solvent mixture of glacial acetic acid (2.0 ml) and carbon tetrachloride (20.0 ml). Bromine (0.8 ml, 13.3 mmol) was added slowly in three portions at 20°C, 6 hours apart, and the reaction was carried out for 5 minutes after addition. The reaction temperature was then maintained at 60°C with continuous stirring for 24 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure. The resulting solid was washed with hot deionized water, filtered and dried to afford 5-bromo-2-furoic acid (3.46 g, 18.1 mmol) in 86% yield. | | References |
[1] Patent: CN106977476, 2017, A. Location in patent: Paragraph 0073-0093
[2] Journal of Materials Chemistry A, 2014, vol. 2, # 18, p. 6589 - 6597
[3] Journal of Pharmaceutical Sciences, 1981, vol. 70, # 10, p. 1095 - 1100
[4] Heterocycles, 1994, vol. 38, # 4, p. 759 - 768
[5] Justus Liebigs Annalen der Chemie, 1953, vol. 580, p. 169,187
[6] Fakhar U. Zaman, M., Mubarik, A., Kanwal, A., Rasool, N., Ahmad, M., Sohail, M., Malik, A., Al-Hussain, S. A., & Zaki, M. E. A. (2025). Facile Synthesis of 4-(Methoxycarbonyl)phenyl 5-Arylfuran-2-Carboxylates via Readily Available Pd Catalyst–Their Thermodynamic, Spectroscopic Features and Nonlinear Optical Behavior. Catalysts, 15(8), 713. https://doi.org/10.3390/catal15080713
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| | 5-Bromofuroic acid Preparation Products And Raw materials |
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