| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
- Rimeporide
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- $40.00
-
2026-04-22
- CAS:187870-78-6
- Purity: 99.98%
- Supply Ability: 10g
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| | Rimeporide Basic information |
| Product Name: | Rimeporide | | Synonyms: | Rimeporide;N-carbamimidoyl-2-methyl-4,5-bis(methylsulfonyl)benzamide;N-(diaminomethylidene)-2-methyl-4,5-bis(methylsulfonyl)benzamide;EMD-87580;Benzamide, N-(aminoiminomethyl)-2-methyl-4,5-bis(methylsulfonyl)-;EMD-87580 >=98% (HPLC);Inhibitor,EMD87580,Sodium-hydrogen Exchanger,Sodium/hydrogen Exchanger,Rimeporide,inhibit,EMD 87580,Na+/H+ Exchanger (NHE);Rimeporide (EMD-87580) | | CAS: | 187870-78-6 | | MF: | C11H15N3O5S2 | | MW: | 333.38 | | EINECS: | | | Product Categories: | | | Mol File: | 187870-78-6.mol |  |
| | Rimeporide Chemical Properties |
| density | 1.55±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMSO : 20 mg/mL (59.99 mM) | | form | powder | | pka | 10.50±0.46(Predicted) | | color | white to beige | | InChI | 1S/C11H15N3O5S2/c1-6-4-8(20(2,16)17)9(21(3,18)19)5-7(6)10(15)14-11(12)13/h4-5H,1-3H3,(H4,12,13,14,15) | | InChIKey | GROMEQPXDKRRIE-UHFFFAOYSA-N | | SMILES | NC(NC(C1=CC(S(=O)(C)=O)=C(S(=O)(C)=O)C=C1C)=O)=N |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | Rimeporide Usage And Synthesis |
| Uses | EMD-87580 has been used as a selective and potent sodium-hydrogen antiporter 1 (NHE-1) inhibitor in cardiac ventricular myocytes to test its effect on the hypertrophic response. | | Biochem/physiol Actions | EMD-87580 is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter. EMD-87580 has shown cardioprotective effects, and has been investigated as a possible treatment for Duchenne′s muscular dystrophy. |
| | Rimeporide Preparation Products And Raw materials |
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