- Mal-PEG2-PFP ester
-
-
2025-06-07
- CAS:1807512-47-5
- Min. Order: 250mg
- Purity: >98.00%
- Supply Ability: 250mg
|
| | Mal-PEG2-PFP Basic information |
| Product Name: | Mal-PEG2-PFP | | Synonyms: | Mal-PEG2-PFP;Mal-PEG2-PFP ester;Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester;perfluorophenyl 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoate;Mal-PEG2-OPFP;Cyclic Peptide Ester Bond Cyclizer | | CAS: | 1807512-47-5 | | MF: | C17H14F5NO6 | | MW: | 423.29 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1807512-47-5.mol |  |
| | Mal-PEG2-PFP Chemical Properties |
| Boiling point | 493.1±45.0 °C(Predicted) | | density | 1.482±0.06 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | -2.34±0.20(Predicted) |
| | Mal-PEG2-PFP Usage And Synthesis |
| Description | Mal-PEG2-PFP is a PEG linker containing maleimide and PFP moieties. Maleimides are thiol-reactive and react between pH 6.5 and 7.5 to form thiolester bonds. PFP moieties are amine-reactive and are less susceptible to undergo hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media. | | Uses | Mal-PEG2-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. | | IC 50 | PEGs; Alkyl/ether |
| | Mal-PEG2-PFP Preparation Products And Raw materials |
|