- Mal-PEG1-PFP ester
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2025-06-07
- CAS:1807530-08-0
- Min. Order: 250mg
- Purity: >98.00%
- Supply Ability: 250mg
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| | Mal-PEG1-PFP Basic information |
| Product Name: | Mal-PEG1-PFP | | Synonyms: | Mal-PEG1-PFP;Mal-PEG1-PFP ester;Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester;perfluorophenyl 3-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)propanoate;Mal-amido-PEG1-PFP Ester;2,3,4,5,6-Pentafluorophenyl 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]propanoate | | CAS: | 1807530-08-0 | | MF: | C15H10F5NO5 | | MW: | 379.24 | | EINECS: | | | Product Categories: | | | Mol File: | 1807530-08-0.mol |  |
| | Mal-PEG1-PFP Chemical Properties |
| Boiling point | 452.8±45.0 °C(Predicted) | | density | 1.541±0.06 g/cm3(Predicted) | | solubility | Soluble in DCM | | pka | -2.34±0.20(Predicted) |
| | Mal-PEG1-PFP Usage And Synthesis |
| Description | Mal-PEG1-PFP is a PEG linker containing maleimide and PFP moieties. Maleimides are thiol-reactive and react between pH 6.5 and 7.5 to form thiolester bonds. PFP moieties are amine-reactive and are less susceptible to undergo hydrolysis. The hydrophilic PEG linker increases the water solubility of a compound in aqueous media. | | Uses | Mal-PEG1-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. | | IC 50 | Alkyl/ether |
| | Mal-PEG1-PFP Preparation Products And Raw materials |
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