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Related articles - How to synthesize fluindapyr?
- Fluindapyr is the latest succinate dehydrogenase inhibitor (SDHI) chiral fungicide with a broad bactericidal spectrum and good....
- Feb 5，2024
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| | fluindapyr Basic information |
| Product Name: | fluindapyr | | Synonyms: | fluindapyr;3-(difluoromethyl)-N-(7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1-methyl-1H-pyrazole-4-carboxamide;1H-Pyrazole-4-carboxamide, 3-(difluoromethyl)-N-(7-fluoro-2,3-dihydro-1,1,3-trimethyl-1H-inden-4-yl)-1-methyl-;Fluindapyr 100 μg/ml Acetonitrile;Fluindapyr 100 μg/mL in Acetonitrile | | CAS: | 1383809-87-7 | | MF: | C18H20F3N3O | | MW: | 351.37 | | EINECS: | 800-189-7 | | Product Categories: | | | Mol File: | 1383809-87-7.mol |  |
| | fluindapyr Chemical Properties |
| | fluindapyr Usage And Synthesis |
| Uses | Fluindapyr is a fungicide, is used to control pests of sugarcane, citrus, rapeseed, and potato plants. | | Definition | ChEBI: 3-(difluoromethyl)-N-(7-fluoro-1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl)-1-methyl-1H-pyrazole-4-carboxamide is a secondary carboxamide resulting from the formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 7-fluoro-1,1,3-trimethylindan-4-amine. It is a member of pyrazoles, a secondary carboxamide, a member of indanes and an organofluorine compound. | | Production Methods | Fluindapyr was produced through a modern, multi-step synthetic route typical of SDHI fungicides, but its commercial production still follows a clear, modular logic. Manufacturers first build the substituted pyrazole core, an established scaffold in contemporary fungicide chemistry, through condensation and cyclisation steps that introduce the key heterocycle with the correct substitution pattern. In parallel, they prepare the distinctive difluoromethyl-substituted aromatic fragment that defines fluindapyr’s potency and lipophilicity. These two intermediates are then coupled through a controlled acylation or related bond-forming step to assemble the full amide structure, with process conditions tuned to avoid decomposition of the sensitive difluoromethyl group. Final purification removes coloured or polymeric by-products common to heterocycle-aryl couplings, yielding technical grade fluindapyr that can be formulated. | | Mechanism of action | Broad-spectrum and systemic. Succinate Dehydrogenase Inhibitor (SDHI). Inhibits the energy production process in pathogenic fungi | | Pesticide Type | Fungicide |
| | fluindapyr Preparation Products And Raw materials |
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