BDP FL-PEG5-propargyl manufacturers
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| | BDP FL-PEG5-propargyl Basic information |
| Product Name: | BDP FL-PEG5-propargyl | | Synonyms: | BDP FL-PEG5-propargyl;Boron, [5-[(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-N-3,6,9,12,15-pentaoxaoctadec-17-yn-1-yl-1H-pyrrole-2-propanamidato-κN1]difluoro-, (T-4)-;BDP FL PEG5 alkyne | | CAS: | 2093197-93-2 | | MF: | C27H38BF2N3O6 | | MW: | 549.42 | | EINECS: | | | Product Categories: | | | Mol File: | 2093197-93-2.mol |  |
| | BDP FL-PEG5-propargyl Chemical Properties |
| solubility | Soluble in DMSO, DMF, DCM | | form | Oil | | color | Brown to black |
| | BDP FL-PEG5-propargyl Usage And Synthesis |
| Description | BDP FL-PEG5-propargyl is a BDP FL linker containing a reactive propargyl group and a hydrophilic PEG spacer arm. The propargyl group allows site-specific conjugation by Click Chemistry and is ideal for conjugation with of antibodies, proteins or probes. The hydrophilic PEG spacer arm can increase water solubility. | | Uses | BDP FL-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | BDP FL-PEG5-propargyl Preparation Products And Raw materials |
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