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| | (S)-(+)-2-(ANILINOMETHYL)PYRROLIDINE Basic information |
| | (S)-(+)-2-(ANILINOMETHYL)PYRROLIDINE Chemical Properties |
| Melting point | 19°C | | Boiling point | 111-112 °C/0.55 mmHg (lit.) | | density | 1.046 g/mL at 25 °C (lit.) | | refractive index | 1.5750 | | Fp | >230 °F | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | sol ether, THF. | | pka | 10.52±0.10(Predicted) | | form | clear liquid | | color | Colorless to Yellow to Green | | Optical Rotation | [α]20/D +19°, c = 1 in ethanol | | Sensitive | Air Sensitive | | BRN | 472065 | | CAS DataBase Reference | 64030-44-0(CAS DataBase Reference) |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 3267 8/PG 2 | | WGK Germany | 3 | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29339900 |
| | (S)-(+)-2-(ANILINOMETHYL)PYRROLIDINE Usage And Synthesis |
| Chemical Properties | Clear colorless viscous liquid | | Synthesis |
(S)-2-(Anilinomethyl)pyrrolidine is prepared by the reaction of (S)-N-(benzyloxycarbonyl)proline with ethyl chloroformate and N-methylmorpholine, aniline, hydrogenolysis with Pd/C, and reduction with LiAlH4 affords the title compound in 59% overall yield.
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| | (S)-(+)-2-(ANILINOMETHYL)PYRROLIDINE Preparation Products And Raw materials |
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