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8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT

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8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT manufacturers
8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Basic information
Product Name:8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
Synonyms:8-bromoadenosine-3’,5’-cyclicmonophosphate(8-br-camp),sodiumsalt;CAMP, 8-BR, NA;ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-BROMO-, SODIUM SALT;8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT;8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT;8-BROMOADENOSINE-3',5'-CYCLOPHOSPHATE SODIUM SALT;8-BROMO-CAMP, NA;8-BROMO-CAMP, SODIUM SALT
CAS:76939-46-3
MF:C10H12BrN5NaO6P
MW:432.1
EINECS:
Product Categories:Cyclic Nucleotide related
Mol File:76939-46-3.mol
8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Structure
8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemical Properties
Melting point >264°C )dec._
storage temp. -20°C
solubility H2O: 100 mg/mL
form powder
color off-white
Water Solubility Soluble in water (100mM)
BRN 7739743
Stability:Hygroscopic, Moisture Sensitive
InChIKeyDMRMZQATXPQOTP-GWTDSMLYSA-M
SMILES[Na+].[P]1(=O)(O[C@@H]2[C@H](O[C@H]([C@@H]2O)[n]3c4ncnc(c4nc3Br)N)CO1)[O-]
Safety Information
Safety Statements 22-24/25
WGK Germany 3
F 10-21
HS Code 29349990
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Usage And Synthesis
Chemical PropertiesOff-white powder
Uses8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt has been used:
  • to study its effect on fas and caspase-3 mRNA expression and on P4 production in bovine mid luteal cell culture
  • used to treat choriocarcinoma BeWo cell line and study its effect on cell viability, apoptosis and morphological changes in the nuclei
  • in superfusion medium for head kidneys stimulation

General Description8-Bromoadenosine 3′:5′-cyclic monophosphate is a brominated cyclic mononucleotide.
Biological ActivityCell-permeable cAMP analog; activator of protein kinase A. Also available as part of the PKA Tocriset™ .
Biochem/physiol ActionsCell-permeable cAMP analog having greater resistance to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells.
storage-20°C (desiccate)
8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT Preparation Products And Raw materials
Tag:8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT(76939-46-3) Related Product Information
Dideoxyadenosine SODIUM AMMONIUM PHOSPHATE DIETHYL PHOSPHATE Ammonium phosphate dibasic Glycerophosphoric acid Sodium Phosphate Monobasic Monohydrate 9-Methyladenine 2-(6-Aminopurin-9-yl)ethanol 2-BROMO-1-ETHOXYMETHYLIMIDAZOLE TRI-AMMONIUM ORTHOPHOSPHATE Vidarabine 8-BROMO-2'-DEOXYADENOSINE 2-Bromo-1-methyl-1H-imidazole 2-Bromo-1H-imidazole Sodium 3-phosphoglycerate DIMETHYL PHOSPHATE Adenine phosphate(1:x) N-BUTYL PHOSPHATE