| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:6β-Prostaglandin I1
CAS:62770-50-7
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:6β-Prostaglandin I1
CAS:62770-50-7
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:6β-Prostaglandin I1
CAS:62770-50-7
Purity:99% Package:1mg;5mg;10mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:6β-Prostaglandin I1
CAS:62770-50-7
Package:10mg/RMB 12600;5mg/RMB 6960;1mg/RMB 1620
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5,6BETA-DIHYDRO PGI2 manufacturers
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| | 5,6BETA-DIHYDRO PGI2 Basic information |
| Product Name: | 5,6BETA-DIHYDRO PGI2 | | Synonyms: | 6BETA-PROSTAGLANDIN I1;6S,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID;5,6BETA-DIHYDRO PGI2;5,6-dihydroprostacyclin;(6S,13E,15S)-6,9α-Epoxy-11α,15-dihydroxyprost-13-en-1-oic acid;RJADQDXZYFCVHV-CBIPHORWSA-N;Prost-13-en-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (6S,9α,11α,13E,15S)- (9CI);6β-Prostaglandin I1 | | CAS: | 62770-50-7 | | MF: | C20H34O5 | | MW: | 354.48 | | EINECS: | | | Product Categories: | | | Mol File: | 62770-50-7.mol |  |
| | 5,6BETA-DIHYDRO PGI2 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: >10 mg/ml; DMSO: >5 mg/ml; Ethanol: >20 mg/ml; PBS pH 7.2: >80 μg/ml | | form | A crystalline solid |
| | 5,6BETA-DIHYDRO PGI2 Usage And Synthesis |
| Description | 6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 μM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.1,2 | | Uses | 6β-Prostaglandin I1 (6β-PGI1) is an analog of prostaglandin I2 (PGI2) that is resistant to hydrolysis in aqueous solutions. 6β-Prostaglandin I1 can reduce gastric acid secretion with an ID50 (dose causing 50% inhibition) of approximately 3.0 μg/kg/min (intravenous injection)[1]. | | Definition | ChEBI: 6-Prostaglandin I1 is a prostanoid. | | References | 1. Whittle, B.J.R., Moncada, S., Whiting, F., et al. Carbacyclin — a potent stable prostacyclin analogue for the inhibition of platelet aggregation Prostaglandins 19(4),605-627(1980).
2. Blair, I.A., Hensby, C.N., and MacDermot, J. Prostacyclin-dependent activation of adenylate cyclase in a neuronal somatic cell hybrid: Prostanoid structure-activity relationships Br. J. Pharmac. 69(3),519-525(1980). |
| | 5,6BETA-DIHYDRO PGI2 Preparation Products And Raw materials |
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