| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
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Product Name:11-deoxy Prostaglandin F1α
CAS:37785-98-1
Purity:>98% Package:1mg;10mg;50mg;100mg;
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:11-deoxy Prostaglandin F1α
CAS:37785-98-1
Purity:99% Package:1mg;5mg;10mg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
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marketing@targetmol.cn |
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Product Name:11-deoxy Prostaglandin F1α
CAS:37785-98-1
Package:1mg/RMB 945;10mg/RMB 7170;5mg/RMB 3960
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| Company Name: |
Cayman Chemical Company
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| Tel: |
800-364-9897 |
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sales@caymanchem.com |
| Products Intro: |
Product Name:11-deoxy Prostaglandin F1α
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11-DEOXY PROSTAGLANDIN F1ALPHA manufacturers
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| | 11-DEOXY PROSTAGLANDIN F1ALPHA Basic information |
| | 11-DEOXY PROSTAGLANDIN F1ALPHA Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: >50 mg/ml (from PGF1a); DMSO: >50 mg/ml (from PGF1a); Ethanol: >75 mg/ml (from PGF1a); PBS pH 7.2: >2 mg/ml (from PGF1a) | | form | A crystalline solid |
| | 11-DEOXY PROSTAGLANDIN F1ALPHA Usage And Synthesis |
| Description | 11-deoxy PGF1α is a synthetic analog of PGF1α. In whole animal studies, a dose of 32 mg/kg inhibited gastric acid secretion by 35%. 11-deoxy PGF1α is also known to cause rat uterine contractions at a dose 0.3 times that of PGF1α. It also exhibits vasopressor and bronchoconstrictor activities at about half the potency of PGF2α in guinea pigs. | | Uses | 11-deoxy Prostaglandin F1α (11-deoxy PGF1α) is an analog of prostaglandin F1α, exhibits side effects on intestines and causes the uterine contraction. 11-deoxy Prostaglandin F1α exhibits activity as vasopressor and bronchoconstrictor[1][2]. | | Definition | ChEBI: 11-Deoxy-PGF1alpha is a prostanoid. | | in vivo | 11-deoxy PGF1α (0-10 mg/kg, i.v., single dose) stimulates the uterine contraction in pregnant SD rats, while reveals slightly efficacy on hamster fertility[1]. | Animal Model: | pregnant Sprague-Dawley rats[1] | | Dosage: | 0-10 mg/kg | | Administration: | i.v., single dose | | Result: | Stimulated uterine contraction 3 times active as PGF1α. |
| | References | [1] Broughton BJ, et al., Uterine stimulant action of some omega-chain modified (+)-11-deoxyprostaglandins. Prostaglandins. 1981 Jul;22(1):53-64. DOI:10.1016/0090-6980(81)90053-8
[2] Hall DW, et al., Structure-activity relationships in a series of 11-deoxy prostaglandins. Prostaglandins. 1976 Mar;11(3):573-87. DOI:10.1016/0090-6980(76)90106-4 |
| | 11-DEOXY PROSTAGLANDIN F1ALPHA Preparation Products And Raw materials |
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