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S-Benzyl-L-cysteine

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CAS:3054-01-1
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CAS:3054-01-1
Purity:99% Package:5KG;1KG Remarks:C10H13NO2S

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  • S-Benzyl-L-cysteine
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  • 2025-07-01
  • CAS:3054-01-1
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  • S-Benzyl-L-cysteine
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  • $1.00 / 1KG
  • 2019-07-06
  • CAS:3054-01-1
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  • Purity: 95%-99.99%
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S-Benzyl-L-cysteine Basic information
Product Name:S-Benzyl-L-cysteine
Synonyms:s-(phenylmethyl)-l-cystein;s-benzylcysteine;3-(BENZYLTHIO)-L-(+)-ALANINE;L-CYSTEINE, S-(PHENYLMETHYL)-;H-CYS(BZL)-OH;H-L-CYS(BZL)-OH;CYSTEINE(BZL)-OH;(S)-BENZYL-L-CYS
CAS:3054-01-1
MF:C10H13NO2S
MW:211.28
EINECS:221-273-4
Product Categories:Amino Acids Derivatives;PROTECTED AMINO ACID & PEPTIDES;Amino Acids;Chiral Reagent;Cysteine [Cys, C];Amino Acids and Derivatives;Cysteine/Cystine;Amino Acid Derivatives;Peptide Synthesis
Mol File:3054-01-1.mol
S-Benzyl-L-cysteine Structure
S-Benzyl-L-cysteine Chemical Properties
Melting point 214 °C (dec.) (lit.)
alpha 26 º (c=0.4, 1N NaOH)
Boiling point 379.2±42.0 °C(Predicted)
density 1.2079 (rough estimate)
refractive index 29 ° (C=1, 1mol/L NaOH)
storage temp. Sealed in dry,Room Temperature
solubility almost transparency in 1mol/L NaOH
pka2.10±0.10(Predicted)
form powder to crystaline
color White to Almost white
Optical Rotation[α]20/D +23°, c = 2 in 1 M NaOH
BRN 1879358
CAS DataBase Reference3054-01-1(CAS DataBase Reference)
EPA Substance Registry SystemL-Cysteine, S-(phenylmethyl)- (3054-01-1)
Safety Information
Risk Statements 36/37/38
Safety Statements 22-24/25-28-26
WGK Germany 3
TSCA Yes
HS Code 29309090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
S-Benzyl-L-cysteine Usage And Synthesis
Chemical PropertiesWHITE POWDER
Usesdetection
peptide synthesis
reaction suitabilityreaction type: solution phase peptide synthesis
Synthesis
L-Cysteine monohydrochloride

52-89-1

Benzyl bromide

100-39-0

S-Benzyl-L-cysteine

3054-01-1

The general procedure for the synthesis of S-benzyl-L-cysteine from L-cysteine hydrochloride and benzyl bromide was as follows: to a rapidly stirred mixture of 2N sodium hydroxide solution (15 mL) and ethanol (35 mL), L-cysteine hydrochloride (1.3 g, 8.2 mmol) and benzyl bromide (0.98 mL, 8.2 mmol) were added sequentially. After the reaction was carried out for 1 h, concentrated hydrochloric acid was slowly added to neutralize the reaction mixture to pH 6-7. Subsequently, the precipitate was collected by filtration and washed sequentially with water, ethanol, and ether to yield S-benzyl-L-cysteine (7) as a white powdery product (1.87 g, 92% yield) with a melting point of 210-212 °C (literature value: 215-216 °C).

References[1] European Journal of Medicinal Chemistry, 2012, vol. 55, p. 176 - 187,12
[2] Journal of Pharmaceutical Sciences, 1984, vol. 73, # 4, p. 559 - 561
[3] Organic Preparations and Procedures International, 1991, vol. 23, # 1, p. 93 - 102
S-Benzyl-L-cysteine Preparation Products And Raw materials
Raw materialsBenzyl chloride-->L-Cysteine monohydrochloride-->Benzyl bromide-->Sodium hydroxide-->Ethanol
Preparation ProductsBUCILLAMINE-->N-(Acetyl-d3)-S-benzyl-L-cysteine
Tag:S-Benzyl-L-cysteine(3054-01-1) Related Product Information
L-Cysteine Benzyl bromide N-Acetyl-L-cysteine H-CYS(BZL)-OME HCL Benzyl alcohol Benzyl benzoate L-Cystine DL-Homocysteine S-BENZYL-L-CYSTEINE 7-AMIDO-4-METHYLCOUMARIN S-BENZYL-L-CYSTEINE BENZYL ESTER HYDROCHLORIDE L-CYSTEINE HCL ANHYDROUS N-alpha-(9-Fluorenylmethyloxycarbonyl)-S-benzyl-L-cysteine N-Fmoc-S-(4-methoxybenzyl)-L-cysteine 2-Amino-3-[(4-methoxybenzyl)thio]propanoic acid Boc-S-(4-methylbenzyl)-L-cysteine NA-BENZYLOXYCARBONYL-S-BENZYL-L-CYSTEINE,N-cbz-S-benzyl-L-cysteine crystalline,N-Benzyloxycarbonyl-S-benzyl-L-cysteine ,Z-S-BENZYL-L-CYSTEINE FMOC-CYS(4-MBZL)-OH FMOC-D-CYS(MBZL)-OH

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