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Bromosulfalein

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Bromosulfalein manufacturers

  • BROMOSULFALEIN
  • BROMOSULFALEIN pictures
  • 2025-12-24
  • CAS:71-67-0
  • Min. Order: 1KG
  • Purity: 98.0%
  • Supply Ability: 10
Bromosulfalein Basic information
Product Name:Bromosulfalein
Synonyms:SODIUM SULFOBROMOPHTHALEIN;SULFOBROMOPHTHALEIN;SULFOBROMOPHTHALEIN DISODIUM SALT;SULFOBROMOPHTHALEIN SODIUM SALT;PHENOLTETRABROMOPHTHALEIN-3',3''-DISULFONIC ACID DISODIUM SALT;disodium 6,6-dihydroxy-3,3-(4,5,6,7-tetrabromo-1,3-dihydro-3-oxoisobenzofuran-1-ylidene)dibenzenesulphonate;disodium phenoltetrabromophthaleindisulphonate;disodium 6,6'-dihydroxy-3,3'-(4,5,6,7-tetrabromo-1,3-dihydro-3-oxoisobenzofuran-1-ylidene)dibenzenesulphonate
CAS:71-67-0
MF:C20H11Br4NaO10S2
MW:818.02
EINECS:200-761-0
Product Categories:Organics
Mol File:71-67-0.mol
Bromosulfalein Structure
Bromosulfalein Chemical Properties
solubility DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: slightly soluble; PBS (pH 7.2): 1 mg/ml
form Powder
color White to off-white
Water Solubility Soluble in water.
Sensitive Moisture Sensitive
Merck 14,8954
Stability:Stable. Incompatible with strong oxidizing agents. May be air or moisture sensitive.
EPA Substance Registry SystemBenzenesulfonic acid, 3,3'-(4,5,6,7-tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis[6-hydroxy-, disodium salt (71-67-0)
Safety Information
Hazard Codes Xn
Risk Statements 42/43
Safety Statements 22-36/37
WGK Germany 3
RTECS SM8395000
TSCA TSCA listed
Hazardous Substances Data71-67-0(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
Bromosulfalein Usage And Synthesis
Chemical Propertieswhite crystalline solid
UsesSulfobromophthalein sodium salt hydrate is a reagent for the quantitative determination of proteins, a dye for liver diagnostics in vitro.
DefinitionChEBI: An organic sodium salt that is the disodium salt of bromosulfophthalein.
Purification MethodsPurify it by TLC on silica Gel G (Merck 250a particle size) in two solvent systems (BuOH/AcOH/H2O 30:7.5:12.5 v/v, and BuOH/propionic acid/H2O 30:20:7.5 v/v). When the solvent reaches a height of ~10cm, the plate is removed, dried in air and developed with NH3 vapour giving blue-coloured spots. Also, the dye can be chromatographed on MN Silica Gel with t-BuOH/H2O/n-BuOH (32:10:5 v/v) as eluent and visualised with a dilute KOH (or NaOH if the Na salt is required) spray. The product corresponding to bromosulfalein is scraped off and eluted with H2O, filtered and evaporated to dryness in a vacuum. It was dissolved in H2O and filtered through Sephadex G-25 and evaporated to dryness. [UV and IR identification: Barbier & DeVeerdt J Pharm Sci 57 819 1968, NMR: Kato et al. Chem Pharm Bull Jpn 20 581 1972, McGuire Anal Biochem 83 75 1977, Beilstein 18/9 V 461.]
Bromosulfalein Preparation Products And Raw materials
Raw materialsPhenol-->Tetrabromophthalic anhydride
Tag:Bromosulfalein(71-67-0) Related Product Information
2,3,5-TRIBROMOBENZOIC ACID 5-Bromo-2-methylbenzoic acid 2-Bromo-6-methylbenzoic acid 1,4-DIBROMO-2-ETHYLBENZENE 2-Bromostyrene 4-Bromo-o-xylene Ethylenesulfonic acid 4-Bromo-2-methylbenzoic acid BROMOSULFALEIN,bromosulfalein sodium 2,5-Dibromobenzaldehyde BROMOSULFALEIN 3,4-Dibromobenzaldehyde Sodium ethylenesulphonate 3-Bromo-2-methylbenzoic acid 2-Bromobenzoic acid 2,5-Dibromotoluene 4-BROMO-2-ETHYLBENZALDEHYDE 2,3-Dimethylbromobenzene