Organ Function Test agent
Drug classification
1. Reagents used for determination of visceral organ function inclcde phosphate histamine, pentagastrin gastrin, phenothiophene, saccharin sodium, sodium bromophthalide, sodium fluorescein, indocyanine green and so on.
2. Diagnostic reagents used in vitro include enzymes and immunological agents, which have various classes, high sensitivity and strong specificity.
Mechanism
The diagnosis mechanism of such drugs is mainly through the reaction of the body or the organs to the drug metabolism to determine whether the function is normal or not.
Clinical application
1. Determination of gastric secretion and pancreatic function, such as histamine.
2. Determination of liver function, such as sodium sulfonyl bromide.
3. Determination of renal function, such as phenol sulfonphthalein.
4. Determination of cardiac circulatory function, such as fluorescein sodium.
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| Structure |
Chemical Name |
CAS |
MF |
 |
Fluorescein Sodium |
518-47-8 |
C20H13NaO5 |
 |
Evans Blue |
314-13-6 |
C34H29N6NaO14S4 |
 |
Congo Red |
573-58-0 |
C32H22N6Na2O6S2 |
 |
Histamine |
51-45-6 |
C5H9N3 |
 |
Phenol Red |
143-74-8 |
C19H14O5S |
 |
Indigo Carmine |
860-22-0 |
C16H11N2NaO8S2 |
 |
ARD 07 |
381231-18-1 |
C26H30N6O3 |
 |
Cortropin Z
|
9050-75-3 |
C207H309N56O59SZn+ |
 |
MEGLUMINE SODIUM IODAMIDE |
58001-89-1 |
C31H40I6N5NaO13 |
 |
TETRAGASTRIN |
1947-37-1 |
C29H36N6O6S |
 |
URACIL-2-13C |
35803-45-3 |
C4H4N2O2 |
 |
alsactide |
34765-96-3 |
C99H155N29O21S |
 |
Bibapcitide |
153507-46-1 |
C112H162N36O43S10 |
 |
Arclofenin |
87071-16-7 |
C19H17ClN2O6 |
 |
Votumumab |
148189-70-2 |
|
 |
Aftobetin |
1208971-05-4 |
C26H32N2O5 |
 |
Impromidine hydrochloride |
65573-02-6 |
C14H24ClN7S |
 |
SECRETIN, HUMAN |
1393-25-5 |
C130H220N44O40 |
|
|
Sulesomab |
167747-19-5 |
|
|
|
Thyrogen |
194100-83-9 |
|
 |
LMI-1195 1037359-47-9 |
1037359-47-9 |
C11H15BrFN3O |
![D-Serine, N,N'-[(3,6-diamino-2,5-pyrazinediyl)dicarbonyl]bis-](/CAS/20200515/GIF/1313706-17-0.gif) |
D-Serine, N,N'-[(3,6-diamino-2,5-pyrazinediyl)dicarbonyl]bis- |
1313706-17-0 |
C12H16N6O8 |
![3H-Indolium, 2-[2-[2-[4-[(2S)-2-[[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]amino]-2-carboxyethyl]phenoxy]-3-[2-[1,3-dihydro-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-2H-indol-2-ylidene]ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-, inner salt, sodium salt (1:4)](/CAS/20211123/GIF/1628858-03-6.gif) |
3H-Indolium, 2-[2-[2-[4-[(2S)-2-[[4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]amino]-2-carboxyethyl]phenoxy]-3-[2-[1,3-dihydro-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-2H-indol-2-ylidene]ethylidene]-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-, inner salt, sodium salt (1:4) |
1628858-03-6 |
C61H68N9NaO17S4 |
 |
Pafolacianine |
1628423-76-6 |
C61H67N9O17S4 |
 |
Capromab Pendetide |
145464-28-4 |
C10H15N5O11P2 |
|
|
Bectumomab |
158318-63-9 |
|
 |
Furomine |
142996-66-5 |
C20H32N2O4 |
 |
MaciMorelin Acetate |
945212-59-9 |
C28H34N6O5 |
 |
DOTA-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-THR-OL (DISULFIDE BRIDGE: 2-7) |
204318-14-9 |
C65H92N14O18S2 |
 |
N-(2,6-DIISOPROPYLPHENYL-CARBAMOYLMETHYL)IMINODIACETIC ACID |
65717-97-7 |
C18H26N2O5 |
|
|
Iodine (124I) Girentuximab |
1011710-99-8 |
|
 |
butilfenin |
66292-52-2 |
C16H22N2O5 |
 |
Tetrofosmin |
127502-06-1 |
C18H40O4P2 |
 |
1841444-25-4 |
1841444-25-4 |
|
 |
ERYTHROSIN B |
49746-10-3 |
C20H6I4Na2O5 |
|
|
Arcitumomab |
154361-48-5 |
|
![(2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-naphthalen-2-yl-propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]-N-[(2R)-2-aminopropanoyl]hexanamide dihydrochloride](/CAS/GIF/158827-34-0.gif) |
(2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-naphthalen-2-yl-propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]-N-[(2R)-2-aminopropanoyl]hexanamide dihydrochloride |
158827-34-0 |
C45H57Cl2N9O6 |
 |
benzylpenicilloyl-polylysine |
31855-75-1 |
C22H32N4O6S |
|
|
Biciromab |
138783-13-8 |
|
 |
TRODAT |
189950-11-6 |
C21H34ClN3S2 |
 |
BZ-TYR-4-ABZ-OH |
37106-97-1 |
C23H20N2O5 |
|
|
corticorelin ovine |
121249-14-7 |
|
 |
IPROFENIN |
66292-53-3 |
C15H20N2O5 |
 |
5(6)-Carboxyfluorescein |
72088-94-9 |
C42H24O14 |
 |
BROMOSULFALEIN |
71-67-0 |
C20H11Br4NaO10S2 |
 |
tolbutamide sodium |
473-41-6 |
C12H18N2NaO3S |
|
|
PTH (1-84) (HUMAN) |
68893-82-3 |
C408H674N126O126S2 |
|
|
Besilesomab |
537694-98-7 |
|
 |
Metyrapone |
908-35-0 |
C22H26N2O13 |
 |
Flortaucipir Impurity 32 |
94153-53-4 |
C18H23FO2 |
 |
Ditiocade sodium |
444190-52-7 |
C5H14NNaO2S2 |
![UREA, [14C]](/CAS/GIF/594-05-8.gif) |
UREA, [14C] |
594-05-8 |
CH4N2O |
![3,3'-(4,5,6,7-tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis[6-hydroxybenzenesulphonic] acid](/CAS/GIF/297-83-6.gif) |
3,3'-(4,5,6,7-tetrabromo-3-oxo-1(3H)-isobenzofuranylidene)bis[6-hydroxybenzenesulphonic] acid |
297-83-6 |
C20H10Br4O10S2 |
|
|
Histoplasmin |
9008-05-3 |
|
 |
Iobitridol |
136949-58-1 |
C20H28I3N3O9 |
 |
BETAZOLE HYDROCHLORIDE |
138-92-1 |
C5H11Cl2N3 |
 |
6-FITC |
3012-71-3 |
C21H11NO5S |
 |
Secretin (human) |
108153-74-8 |
C130H220N44O40 |
 |
Saccharin sodium dihydrate |
6155-57-3 |
C7H8NNaO4S |
|
|
IOBITRIDOL |
|
|
 |
Sulfobromophthalein sodium |
123359-42-2 |
C20H13Br4NaO11S2 |
 |
Fluorescein isothiocyanate |
27072-45-3 |
C21H11NO5S |
 |
SACCHARIN SODIUM SALT DIHYDRATE |
82385-42-0 |
C7H8NNaO4S |
 |
P-AMINOHIPPURIC ACID SODIUM SALT |
94-16-6 |
C9H11N2NaO3 |
 |
PENTAGASTRIN |
5534-95-2 |
C37H49N7O9S |
 |
Perfluoro-2-methylbutane |
594-91-2 |
C5F12 |
![Ferri (59 Fe) citratis injectio [INN-Latin]](/CAS/20180808/GIF/54063-42-2.gif) |
Ferri (59 Fe) citratis injectio [INN-Latin]
|
54063-42-2 |
C6H5FeO7 |
 |
Aftobetin Hydrochloride |
1353222-83-9 |
C26H33ClN2O5 |
 |
flutemetamol ((18)F) |
765922-62-1 |
C14H11FN2OS |
 |
Saccharin sodium |
128-44-9 |
C7H5NNaO3S |
 |
HISTAMINE DIPHOSPHATE |
23297-93-0 |
C5H12N3O4P |
 |
METYRAPONE |
54-36-4 |
C14H14N2O |
 |
Indocyanine green |
3599-32-4 |
C43H49N2NaO6S2 |
 |
betazole |
105-20-4 |
C5H9N3 |