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| | MAG-FURA-2, AM Basic information |
| Product Name: | MAG-FURA-2, AM | | Synonyms: | Fura 2-AM magnesium-selective analog;MAFENIDEACETATE;FURA 2-AM magnesium selective analogue;2-[5-[2-(acetoxymethoxy)-2-keto-ethoxy]-6-[bis[2-(acetoxymethoxy)-2-keto-ethyl]amino]benzofuran-2-yl]oxazole-5-carboxylic acid acetoxymethyl ester;acetyloxymethyl 2-[5-[2-(acetyloxymethoxy)-2-oxo-ethoxy]-6-[bis[2-(acetyloxymethoxy)-2-oxo-ethyl]amino]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate;acetyloxymethyl 2-[5-[2-(acetyloxymethoxy)-2-oxoethoxy]-6-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate;Mag-Fura 2, AM Cell PerMeant;Furaptra, AM ester [Known as Mag-Fura-2, AM ester, TM of Molecular Probes] | | CAS: | 130100-20-8 | | MF: | C30H30N2O19 | | MW: | 722.56 | | EINECS: | | | Product Categories: | Benzofuran | | Mol File: | 130100-20-8.mol |  |
| | MAG-FURA-2, AM Chemical Properties |
| Melting point | >200℃ | | Boiling point | 797.5±70.0 °C(Predicted) | | density | 1.436±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Insoluble in water; soluble in dimethyl sulfoxide, ethyl acetate | | pka | -2.19±0.10(Predicted) | | form | powder | | color | Light yellow | | Appearance | Solid Powder | | λmax | 366 nm | | Biological Applications | Magnesium indicator; calcium indicator; zinc indicator |
| | MAG-FURA-2, AM Usage And Synthesis |
| Description | Mag-fura-2 AM is a membrane-permeant, short-wavelength fluorescent indicator for intracellular magnesium. It can be loaded into cells via incubation, and hydrolyzed to mag-fura-2. Intracellular magnesium concentration can be measured by ratio of fluorescence intensity generated by mag-fura-2. | | Uses | Calcium is an important part of the human body, usually in the form of calcium, a large number of bones and teeth of the human body, a small amount of blood and tissues.
MCE calcium ion detection probe can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence, in addition, Mag-indo-1/AM and Mag-Fluo-4 AM at a certain concentration (usually 5 mM) can effectively identify intracellular magnesium ions[1]. | | storage | Store at -20°C | | References | [1] García-Martín E, et, al. Intrasynaptosomal free Mg2+ concentration measured with the fluorescent indicator mag-fura-2: modulation by Na+ gradient and by extrasynaptosomal ATP. J Neurochem. 1995 Dec;65(6):2757-64. DOI:10.1046/j.1471-4159.1995.65062757.x | | Excitation / Emission Maximum | 537 nm/559 ±5 nm |
| | MAG-FURA-2, AM Preparation Products And Raw materials |
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