Mag-indo 1-am

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Mag-indo 1-am Basic information
Product Name:Mag-indo 1-am
Synonyms:INDO 1-AM ANALOG;indo 1-am analog selective for*magnesium;MAG-INDO 1-AM, 10X50 UG*;Mag-indo-1 Am Ester;Mag-indo-1 Acetoxymethyl Ester;Mag-indo 1-am
CAS:130926-94-2
MF:C30H32N2O12
MW:612.58128
EINECS:
Product Categories:Indole
Mol File:130926-94-2.mol
Mag-indo 1-am Structure
Mag-indo 1-am Chemical Properties
Melting point >200℃
storage temp. 2-8°C
solubility DMSO: soluble
form powder
color Pale yellow
λmax354 nm
Biological ApplicationsMagnesium indicator; calcium indicator
Safety Information
WGK Germany 3
F 3-8-10
MSDS Information
Mag-indo 1-am Usage And Synthesis
Description

Mag-indo-1 AM is a membrane-permeant fluorescent indicator for intracellular magnesium. It can be loaded into cells via incubation, and hydrolyzed to mag-indo-1 by cytosilic esterases.

UsesMag-indo-1/AM is a cell-permeable fluorescent indicator for Mg2+ and also for Ca2+ (Ex=340-390 nm, Em=410-490 nm). Mag-indo-1/AM can be used to determine intracellular Mg2+ and Ca2+ concentrations[1][2].
References[1] Griffiths EJ. Calcium handling and cell contraction in rat cardiomyocytes depleted of intracellular magnesium. Cardiovasc Res. 2000 Jul;47(1):116-23. DOI:10.1016/s0008-6363(00)00061-4
[2] Morelle B, et al. Measurement of intracellular magnesium concentration in 3T3 fibroblasts with the fluorescent indicator Mag-indo-1. Anal Biochem. 1994 Apr;218(1):170-6. DOI:10.1006/abio.1994.1156
Excitation / Emission Maximum537 nm/559 ±5 nm
Mag-indo 1-am Preparation Products And Raw materials
Tag:Mag-indo 1-am(130926-94-2) Related Product Information
Indo 1 tetrapotassium salt Indo 1-am MAG-FURA-2, AM Indigo Carmine INDO 1 PENTAPOTASSIUM SALT 4',6-Diamidino-2-phenylindole dihydrochloride Glycine,N-[2-(carboxymethoxy)-4-[[(2',7'-dichloro-3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)carbonyl]amino]phenyl]-N-(carboxymethyl)-,potassium salt (1:5) 4-(1H-Indol-2-yl)-phenylamine Mag-indo 1-am 1H-Indole-6-carboxylic acid, 2-phenyl-, methyl ester 6-methyl-2-phenyl-1H-indole