2,5-Diaminopyrimidine manufacturers
- 2,5-Diaminopyrimidine
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- $1.10
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2026-08-20
- CAS:22715-27-1
- Min. Order: 1g
- Purity: 99.00%
- Supply Ability: 100 Tons Min
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| | 2,5-Diaminopyrimidine Basic information |
| | 2,5-Diaminopyrimidine Chemical Properties |
| Melting point | 200 °C | | Boiling point | 401.7±37.0 °C(Predicted) | | density | 1.368±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 4.83±0.10(Predicted) | | Appearance | Yellow to brown Solid |
| | 2,5-Diaminopyrimidine Usage And Synthesis |
| Synthesis | Synthesis of I-5: To a 1L round bottom flask was added 5-nitropyrimidin-2-amine (30 g, 214.13 mmol, 1.00 eq.), methanol (400 mL) and palladium carbon (12 g). The reaction mixture was stirred overnight at room temperature in a hydrogen atmosphere. Upon completion of the reaction, the solid catalyst was removed by filtration. The filtrate was concentrated under reduced pressure to afford pyrimidine-2,5-diamine (20 g, 85% yield) as a light brown solid. | | References | [1] Patent: US7235559, 2007, B1
[2] Patent: US2014/275119, 2014, A1. Location in patent: Paragraph 0416
[3] Journal of the American Chemical Society, 1942, vol. 64, p. 2340
[4] Journal of Medicinal Chemistry, 2008, vol. 51, # 6, p. 1681 - 1694
[5] Patent: WO2010/111483, 2010, A1. Location in patent: Page/Page column 90 |
| | 2,5-Diaminopyrimidine Preparation Products And Raw materials |
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