| Company Name: |
Alfa Aesar |
| Tel: |
400-6106006 |
| Email: |
saleschina@alfa-asia.com |
| Company Name: |
Energy Chemical |
| Tel: |
400-0056266 |
| Email: |
sales8178@energy-chemical.com |
3-Bromo-5-ethoxy-4-hydroxybenzaldehyde manufacturers
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| | 3-Bromo-5-ethoxy-4-hydroxybenzaldehyde Basic information |
| | 3-Bromo-5-ethoxy-4-hydroxybenzaldehyde Chemical Properties |
| Melting point | 141-143°C | | Boiling point | 303.8±37.0 °C(Predicted) | | density | 1.568±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | 6.39±0.23(Predicted) | | Appearance | White to off-white Solid | | Sensitive | Air Sensitive | | CAS DataBase Reference | 3111-37-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36/37/39 | | HazardClass | IRRITANT | | HS Code | 2913000090 |
| Provider | Language |
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ALFA
| English |
| | 3-Bromo-5-ethoxy-4-hydroxybenzaldehyde Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 3-bromo-5-ethoxy-4-hydroxybenzaldehyde from the compound (CAS: 1567388-59-3): a mixture of substrate 1a (1 mmol), cobalt salt (n1 mol%), and NaOH (n2 equivalents) in ethylene glycol (EG, 5 mL) was stirred and reacted for 8 hr at 80 °C under oxygen (1 atm) atmosphere. Upon completion of the reaction, hydrochloric acid (10 mL, 2%) and methyl tert-butyl ether (MTBE, 10 mL) were sequentially added to the reaction mixture. The organic layer was separated and the aqueous phase was further extracted with MTBE (10 mL x 2). All organic phases were combined, dried with anhydrous sodium sulfate and concentrated to obtain the residue. The residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate, 10:1) to afford the target product 3-bromo-5-ethoxy-4-hydroxybenzaldehyde (2a). | | References | [1] Tetrahedron Letters, 2014, vol. 55, # 8, p. 1406 - 1411 |
| | 3-Bromo-5-ethoxy-4-hydroxybenzaldehyde Preparation Products And Raw materials |
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