Mal-amido-PEG8-val-gly-PAB-OH

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Mal-amido-PEG8-val-gly-PAB-OH manufacturers
Mal-amido-PEG8-val-gly-PAB-OH Basic information
Product Name:Mal-amido-PEG8-val-gly-PAB-OH
Synonyms:Mal-amido-PEG8-val-gly-PAB-OH
CAS:2353409-52-4
MF:C40H63N5O15
MW:853.95
EINECS:
Product Categories:ADC LINKER
Mol File:2353409-52-4.mol
Mal-amido-PEG8-val-gly-PAB-OH Structure
Mal-amido-PEG8-val-gly-PAB-OH Chemical Properties
Boiling point 1051.3±65.0 °C(Predicted)
density 1.231±0.06 g/cm3(Predicted)
pka14.14±0.46(Predicted)
Safety Information
MSDS Information
Mal-amido-PEG8-val-gly-PAB-OH Usage And Synthesis
UsesMal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
IC 50Cleavable Linker
References[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
Mal-amido-PEG8-val-gly-PAB-OH Preparation Products And Raw materials
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