1,2-Dihydro-3H-1,2,4-triazol-3-one

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CAS:930-33-6
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1,2-Dihydro-3H-1,2,4-triazol-3-one Basic information
Product Name:1,2-Dihydro-3H-1,2,4-triazol-3-one
Synonyms:1,2,4-Triazole-3-ol;1,2-dihydro-3h-1,2,4-triazol-3-one;1,2-DIHYDRO-3H-1,2,4-TRIAZOLE-3-ONE;1,2-Dihydro-3H-1,2,4-triazole-;1,2,4-TRIAZOL-3-ONE (SEE 5130);2,4-Dihydro-1,2,4-triazol-3-one;s-Triazol-3-ol;Δ2-1,2,4-Triazolin-5-one
CAS:930-33-6
MF:C2H3N3O
MW:85.06
EINECS:213-214-6
Product Categories:
Mol File:930-33-6.mol
1,2-Dihydro-3H-1,2,4-triazol-3-one Structure
1,2-Dihydro-3H-1,2,4-triazol-3-one Chemical Properties
Melting point 234-235 °C
Boiling point 270℃[at 101 325 Pa]
density 1.81±0.1 g/cm3(Predicted)
vapor pressure 0.003Pa at 25℃
storage temp. Inert atmosphere,Room Temperature
solubility DMSO (Sparingly), Methanol (Slightly, Sonicated)
pka8.81±0.20(Predicted)
form crystals
color White
Water Solubility 76g/L at 20℃
LogP0 at 35℃
NIST Chemistry Reference3H-1,2,4-Triazol-3-one, 1,2-dihydro-(930-33-6)
EPA Substance Registry System3H-1,2,4-Triazol-3-one, 1,2-dihydro- (930-33-6)
Safety Information
TSCA TSCA listed
HS Code 2933998090
MSDS Information
1,2-Dihydro-3H-1,2,4-triazol-3-one Usage And Synthesis
Chemical Propertieswhite solid
Flammability and ExplosibilityNot classified
Synthesis
Semicarbazide hydrochloride

563-41-7

1,2-Dihydro-3H-1,2,4-triazol-3-one

930-33-6

Example 2 Synthesis of 1,2,4-triazolin-5-one: A mixture of aminourea hydrochloride (10.0 g, 89.6 mmol), trimethyl orthoformate (28.5 g, 269 mmol), and methanol (100 mL) was stirred for 2 hours at room temperature. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure. Subsequently, toluene (100 mL) was added to the concentrate and the mixture was cooled to 0°C. The precipitate was collected by filtration to afford 1,2-dihydro-3H-1,2,4-triazol-3-one (7.26 g, 100% yield) as a white solid. The structure of the product was confirmed by 1H NMR (d6-DMSO) and 13C NMR (d6-DMSO): 1H NMR δ= 7.66 (1H, s, CH), 11.24 (1H, s, NH) and 11.35 (1H, s, NH); and 13C NMR δ= 137.0 (CH2C=N) and 156.6 (NHCONH).

References[1] Patent: US2003/187274, 2003, A1
1,2-Dihydro-3H-1,2,4-triazol-3-one Preparation Products And Raw materials
Raw materialsSemicarbazide hydrochloride-->Toluene-->Trimethoxymethane-->Methanol
Tag:1,2-Dihydro-3H-1,2,4-triazol-3-one(930-33-6) Related Product Information
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