1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea

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1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea manufacturers

  • TMP-153
  • TMP-153 pictures
  • $293.00
  • 2026-07-13
  • CAS:128831-46-9
  • Purity: 99.87%
  • Supply Ability: 10g
1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea Basic information
Product Name:1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea
Synonyms:1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea;Urea, N-[4-(2-chlorophenyl)-6,7-dimethyl-3-quinolinyl]-N'-(2,4-difluorophenyl)-;TMP153,TMP 153;N-(4-(2-chlorophenyl)-6,7-dimethyl-3-quinolyl)-N'-(2,4-difluorophenyl)urea
CAS:128831-46-9
MF:C24H18ClF2N3O
MW:437.87
EINECS:
Product Categories:
Mol File:128831-46-9.mol
1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea Structure
1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea Chemical Properties
Melting point approximate 217℃
storage temp. Store at -20°C
solubility DMF: 10 mg/ml,DMSO: 30 mg/ml
form White solid.
Safety Information
MSDS Information
1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea Usage And Synthesis
UsesTMP-153 is an orally active inhibitor of ACAT with an IC50 value of approximately 5-10 nM against hepatic and intestinal ACAT in varicose animals. TMP-153 exhibits cholesterol-lowering effects and can be utilized in the research of atherosclerosis[1].
References[1] Sugiyama Y, et al. TMP-153, a novel ACAT inhibitor, inhibits cholesterol absorption and lowers plasma cholesterol in rats and hamsters. Atherosclerosis. 1995;113(1):71-78. DOI:10.1016/0021-9150(94)05429-m
1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea Preparation Products And Raw materials
Tag:1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea(128831-46-9) Related Product Information
pyripyropene A 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) S-nitrosocaptopril Abz-Phe-Arg-Lys(Dnp)-Pro-OH 1-[4-(2-chlorophenyl)-6,7-dimethyl-quinolin-3-yl]-3-(2,4-difluoropheny l)urea 4-Hydroxy-L-phenylglycine