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| | 4,7-Dichloro-1,10-phenanthroline Basic information | | Application |
| Product Name: | 4,7-Dichloro-1,10-phenanthroline | | Synonyms: | 4,7-Dichloro-1,10-phenanthroline;4,7-Dichloro-o-phenanthroline;NSC 626;1,10-Phenanthroline,4,7-dichloro;4,7-Dichloro-1,10-phenanthroline Hydrate;4,7-Dichloro-1,10-phenanthroline 97%;4,7-Dichloro-1,10-phenthroline;4,7-Dichloro-1,10-phenanthroline Hydrate > | | CAS: | 5394-23-0 | | MF: | C12H6Cl2N2 | | MW: | 249.1 | | EINECS: | | | Product Categories: | Building Blocks;Catalysis and Inorganic Chemistry;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;N-Containing;Other Ligands;N-ContainingChemical Synthesis;Other LigandsHeterocyclic Building Blocks;Catalysis and Inorganic Chemistry;Halogenated Heterocycles;Heterocyclic Building Blocks;Others | | Mol File: | 5394-23-0.mol |  |
| | 4,7-Dichloro-1,10-phenanthroline Chemical Properties |
| Melting point | 243-247 °C | | Boiling point | 395.9±37.0 °C(Predicted) | | density | 1.482±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | form | solid | | pka | 3.29±0.10(Predicted) | | color | white to tan | | InChI | InChI=1S/C12H6Cl2N2/c13-9-3-5-15-11-7(9)1-2-8-10(14)4-6-16-12(8)11/h1-6H | | InChIKey | GIEQBYJCGYHHSU-UHFFFAOYSA-N | | SMILES | N1C2C(=CC=C3C=2N=CC=C3Cl)C(Cl)=CC=1 |
| Hazard Codes | Xn | | Risk Statements | 22-37/38-41 | | Safety Statements | 26-39 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 3 | | TSCA | No | | HazardClass | 6.1 | | HS Code | 29339900 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3 |
| | 4,7-Dichloro-1,10-phenanthroline Usage And Synthesis |
| Application | 1,10-phenanthroline can be used as an intermediate in fluorescent materials, mainly in the fields of life sciences and medicine, catalysis, and novel optoelectronic materials. | | Synthesis | Take 4.16g (10mmol) of 1,2-bis-[(2,2-dimethyl-4,6-dioxo-1,3-dioxane-5-ylidenemethyl)amino]benzene in 300mL of p-phenylene ether reflux for 30min, the mixture was cooled down to room temperature, when added to cyclohexane there was a large amount of precipitate precipitation precipitation, filtration and washed out of the p-phenylene ether with cyclohexane, vacuum drying to obtain 32.43g of light yellow powder crude The product was dried under vacuum to give 32.43g of light yellow powder crude product with a yield of about 99%. This product does not need to be purified, and can be directly carried out the next step of the reaction. Take 2.1g (10mmol) 4,7-dioxo-1,10-o-phenanthroline, add to 60g (210mmo1) phosphorus trichloride, under the protection of nitrogen reaction for 30min, the reaction solution was poured into 400mL of ice-water mixture, adjusted to pH 7-8 with 10% NaOH, extracted with dichloromethane (100mLx3), the organic layer was combined, dried with anhydrous magnesium sulfate, rotary evaporation with column chromatography. Drying, rotary evaporation and column chromatography gave 1.74 g of white powder product 4,7-dichloro-1,10-phenanthroline in 70% yield. |
| | 4,7-Dichloro-1,10-phenanthroline Preparation Products And Raw materials |
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