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N-Carbobenzyloxy-L-proline methyl ester

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N-Carbobenzyloxy-L-proline methyl ester Basic information
Product Name:N-Carbobenzyloxy-L-proline methyl ester
Synonyms:N-Z-L-proline methyl ester, 97%;N-Z-L-proline methyl ester 97%;S-1-CBZ-Pyrrolidine-2-carboxylic acid Methyl Ester CBZ-D-Proline Methyl Ester;Cbz-Pro-Ome;(2S)-2-Methyl-1,2-pyrrolidinedicarboxylic Acid 1-(Phenylmethyl) Ester;N-Cbz proline methylester;(S)-1-Benzyl 2-Methyl pyrrolidine-1,2-dicarboxylate;N-Benzyloxycarbonyl-L-proline Methyl ester
CAS:5211-23-4
MF:C14H17NO4
MW:263.29
EINECS:
Product Categories:Amino Acid Derivatives;Peptide Synthesis;Proline
Mol File:5211-23-4.mol
N-Carbobenzyloxy-L-proline methyl ester Structure
N-Carbobenzyloxy-L-proline methyl ester Chemical Properties
Boiling point 375.0±42.0 °C(Predicted)
density 1.175 g/mL at 25 °C (lit.)
refractive index n20/D 1.5217(lit.)
Fp >230 °F
storage temp. 2-8°C
form Liquid
pka-3.40±0.40(Predicted)
color Colorless to light yellow
Optical Rotation[α]22/D 36.8°, neat
Major Applicationpeptide synthesis
InChI1S/C14H17NO4/c1-18-13(16)12-8-5-9-15(12)14(17)19-10-11-6-3-2-4-7-11/h2-4,6-7,12H,5,8-10H2,1H3/t12-/m0/s1
InChIKeyBLQYEDXWEDWCNJ-LBPRGKRZSA-N
SMILESCOC(=O)[C@@H]1CCCN1C(=O)OCc2ccccc2
Safety Information
Hazard Codes Xi
Risk Statements 36/38
Safety Statements 26-37/39
WGK Germany 3
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
MSDS Information
ProviderLanguage
SigmaAldrich English
N-Carbobenzyloxy-L-proline methyl ester Usage And Synthesis
Usespeptide synthesis
reaction suitabilityreaction type: solution phase peptide synthesis
N-Carbobenzyloxy-L-proline methyl ester Preparation Products And Raw materials
Preparation ProductsL-(+)-Glutamic acid hydrochloride
Tag:N-Carbobenzyloxy-L-proline methyl ester(5211-23-4) Related Product Information
N-Cbz-L-proline tert-butyl ester Z-Hyp-OMe CIS-ZHPROME (2S, 4S)-4-AMINO-1-[BENZYLOXYCARBONYL]PYRROLIDINE-2-METHYLCARBOXYLATE HYDROCHLORIDE Ethyl (S)-1-Cbz-4-hydroxy-2-pyrrolidinecarboxylate (2S, 4R)-4-AMINO-1-[BENZYLOXYCARBONYL]PYRROLIDINE-2-METHYLCARBOXYLATE HYDROCHLORIDE Z-PYR-ONP Z-PRO-ONP (+)-N-Carbobenzyloxy-D-proline methyl ester N-Carbobenzyloxy-L-proline methyl ester (2S,4S)-1-N-Cbz-4-mercaptopyrrolidine-2-carboxylic acid benzyl ester Cbz-Pyr-OEt 1-Cbz-4(R)-hydroxypyrrolidine-2-carboxylic acid ethyl ester (2S,4R)-1-Cbz-4-amino pyrrolidine-2-carboxylic acid methyl ester CBZ-PYR-OME 1,2,4-pyrrolidinetricarboxylic acid, 2-(1H-pyrazol-1-ylmethyl)-5-(2-thienyl)-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester, (2R,4S,5R)- 1,2,4-pyrrolidinetricarboxylic acid, 5-(5-oxazolyl)-2-(1H-pyrazol-1-ylmethyl)-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester, (2R,4S,5R)- Ethyl (S)-1-Cbz-4-oxo-2-pyrrolidinecarboxylate