ChemicalBook > Product Catalog >Biochemical Engineering >Biochemical Reagents >Agonist Inhibitors >N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide

N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide

Request For Quotation
N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide Suppliers list
Company Name: Chembest Research Laboratories Limited  
Tel: 021-20908456
Email: sales@BioChemBest.com
Company Name: Haoyuan Chemexpress Co., Ltd.  
Tel: 021-58950125
Email: info@chemexpress.com
Company Name: EnliPharma Technology Co., Ltd  
Tel: 0551-66399836 18955197623
Email: sales@enlipharma.com
Company Name: AdooQ BioScience, LLC   
Tel: +1 (866) 930-6790
Email: info@adooq.com
Company Name: Shanghai Tombiopharma Chemical Co. Ltd.  
Tel: 13391076197
Email: tombiopharma@163.com

N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide manufacturers

  • BMS-509744
  • BMS-509744 pictures
  • $1060.00
  • 2026-07-14
  • CAS:439575-02-7
  • Purity: 99.70%
  • Supply Ability: 10g
  • BMS-509744
  • BMS-509744 pictures
  • 2026-07-01
  • CAS:439575-02-7
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 20Tons
  • BMS-509744
  • BMS-509744 pictures
  • $662.00
  • 2025-12-17
  • CAS:439575-02-7
  • Purity: 99.70%
  • Supply Ability: 10g
N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide Basic information
Product Name:N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide
Synonyms:BMS 509744;N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide;N-[5-[[5-[(4-Acetyl-1-piperazinyl)carbonyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[[(1,2,2-trimethylpropyl)amino]methyl]benzamide;BMS-509744 (BMS 509744;Benzamide, N-[5-[[5-[(4-acetyl-1-piperazinyl)carbonyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[[(1,2,2-trimethylpropyl)amino]methyl]-;Benzamide （BMS-509744）
CAS:439575-02-7
MF:C32H41N5O4S2
MW:623.83
EINECS:
Product Categories:
Mol File:439575-02-7.mol
N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide Structure
N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide Chemical Properties
density 1.28
storage temp. Store at -20°C
solubility Soluble in DMSO
form solid
pka6.65±0.50(Predicted)
color White
InChIKeyZHXNIYGJAOPMSO-UHFFFAOYSA-N
SMILES[s]1c(ncc1Sc3c(cc(c(c3)C(=O)N4CCN(CC4)C(=O)C)OC)C)NC(=O)c2ccc(cc2)CNC(C(C)(C)C)C
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide Usage And Synthesis
UsesBMS 509744, is a potent and selective interleukin-2 inducible T cell kinase (ITK) inhibitor. It reduces HIV infection of primary CD4+ T cells, and in vitro.
DefinitionChEBI: N-[5-[[5-[(4-acetyl-1-piperazinyl)-oxomethyl]-4-methoxy-2-methylphenyl]thio]-2-thiazolyl]-4-[(3,3-dimethylbutan-2-ylamino)methyl]benzamide is a member of benzamides.
Biological ActivityCell permeable: yes', 'Primary Target
ITK', 'Target IC50: 19 nM for ITK
in vivo

BMS-509744 and BMS-488516 suppress the production of IL-2 induced by anti-T-cell receptor antibody administered to mice. BMS-509744 exhibits a 50% inhibitory capacity when dosed at 50 mg/kg, irrespective of the amount of induction antibody. BMS-509744 also significantly diminishes lung inflammation in a mouse model of ovalbumin-induced allergy/asthma[1].

N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide Preparation Products And Raw materials
Tag:N-(5-((5-(4-Acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl)thio)thiazol-2-yl)-4-(((3,3-dimethylbutan-2-yl)amino)methyl)benzamide(439575-02-7) Related Product Information
N-Boc-hexahydro-5-oxocyclopenta[c]pyrrole N-Acetyl-alpha-D-glucosamine N-(3-Hydroxypropyl)ethylenediamine N-{4-[(2-Aminopyridin-4-yl)oxy]-3-fluorophenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide N-BOC-6-azaspiro[3.4]octan-2-ol CP-456773 sodium N-[(1R)-1-(Aminomethyl)-2-[(3S)-tetrahydro-2H-pyran-3-yl]ethyl]-N-methylcarbamic acid tert-butyl ester MK-8617 N,N'-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine 1,1'-bis[2-(octyloxy)ethyl] ester N-BOC-cis-4-fluoro-L-proline MG-132 SRT1720 N-(8-Benzyl-8-azabicyclo[3.2.1]oct-3-yl-exo)-2-methylpropanamide N-Boc-3-piperidineacetic acid N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine N-Boc-exo-3-aminotropane N-Boc-endo-3-aminotropane