- LDHA-IN-4
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- $44.00
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2026-07-15
- CAS:1370290-34-8
- Purity: 99.68%
- Supply Ability: 10g
- AZ-33
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- $1.00
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2024-10-22
- CAS:1370290-34-8
- Min. Order: 1KG
- Purity: MIn98%HPLC/LC
- Supply Ability: 100KGS
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| Product Name: | AZ-33 | | Synonyms: | AZ-33;AZ-33(AZ33);2-(4-(4-((3-((2-methylbenzo[d]thiazol-6-yl)amino)-3-oxopropyl)amino)-4-oxobutyl)benzyl)malonic acid;2-[[4-[4-[[3-[(2-Methyl-6-benzothiazolyl)amino]-3-oxopropyl]amino]-4-oxobutyl]phenyl]methyl]propanedioic acid;AZ-33;AZ33;AZ 33;LDHA Inhibitor;Propanedioic acid, 2-[[4-[4-[[3-[(2-methyl-6-benzothiazolyl)amino]-3-oxopropyl]amino]-4-oxobutyl]phenyl]methyl]-;LDHA-IN-4 | | CAS: | 1370290-34-8 | | MF: | C25H27N3O6S | | MW: | 497.56 | | EINECS: | | | Product Categories: | | | Mol File: | 1370290-34-8.mol |  |
| | AZ-33 Chemical Properties |
| Boiling point | 843.9±65.0 °C(Predicted) | | density | 1.381±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | DMF: 30mg/mL; DMSO: 30mg/mL; Ethanol: 2mg/mL; PBS (pH 7.2): slight | | form | A crystalline solid | | pka | 3.21±0.10(Predicted) | | color | White to off-white |
| | AZ-33 Usage And Synthesis |
| Uses | AZ-33 is a selective lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 0.5 μM and a Kd of 0.093 μM[1]. | | References | [1] Ward RA,et al. Design and synthesis of novel lactate dehydrogenase A inhibitors by fragment-based lead generation. J Med Chem. 2012 Apr 12;55(7):3285-306. DOI:10.1021/jm201734r |
| | AZ-33 Preparation Products And Raw materials |
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