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| | Edoxaban Impurity 16 Basic information |
| Product Name: | Edoxaban Impurity 16 | | Synonyms: | TERT-BUTYL {(1R,2S,5S)-2-AZIDO-5-[(DIMETHYLAMINO)CARBONYL]CYCLOHEXYL}CARBAMATE;Edoxaban Azido t-BOC Impurity;carbamic acid, [(1R,2S,5S)-2-azido-5-[(dimethylamino)carbonyl]cyclohexyl]-, 1,1-dimethylethyl ester;tert-butylN-[(1R,2S,5S)-2-azido-5-(dimethylcarbamoyl)cyclohexyl]carbamate;SWF-30;Edoxaban Impurity 16 (1R,2S,5S);Yidu Saban Impurity 33;Edoxaban Intermediate A8 | | CAS: | 480450-69-9 | | MF: | C14H25N5O3 | | MW: | 311.38 | | EINECS: | | | Product Categories: | | | Mol File: | 480450-69-9.mol |  |
| | Edoxaban Impurity 16 Chemical Properties |
| storage temp. | Store at 0-8 °C | | InChI | InChI=1/C14H25N5O3/c1-14(2,3)22-13(21)16-11-8-9(12(20)19(4)5)6-7-10(11)17-18-15/h9-11H,6-8H2,1-5H3,(H,16,21)/t9-,10-,11+/s3 | | InChIKey | LVJZCKRMMBTVNC-FRQGNSTANA-N | | SMILES | C(OC(C)(C)C)(=O)N[C@@H]1C[C@@H](C(=O)N(C)C)CC[C@@H]1N=[N+]=[N-] |&1:8,10,18,r| |
| | Edoxaban Impurity 16 Usage And Synthesis |
| | Edoxaban Impurity 16 Preparation Products And Raw materials |
| Raw materials | 1S,3R,4S)-(+)-4-azido-3-[(tert-butoxycarbonyl)aMino]cyclohexanecarboxylic acid ethyl ester-->(1s,3r,4r)-3-[(tert-butoxycarbonyl)amino]-4-[(methylsulfonyl)oxy]cyclohexanecarboxylic acid ethyl ester-->(1S,3R,4R)-3-(Boc-aMino)-4-hydroxy-cyclohexanecarboxylic acid ethyl ester-->ethyl (1R,4S,6S)-7-oxabicyclo[4.1.0]heptane-4-carboxylate-->(1S,4S,5S)-4-Bromo-6-oxabicyclo[3.2.1]octan-7-one-->(S)-(-)-3-Cyclohexenecarboxylic acid-->(1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate-->(1S,3R,4R)-3-amino-4-hydroxy-N,N-dimethylcyclohexanecarboxamide-->carbamic acid, n-[(1r,2r,5s)-5-[(dimethylamino)carbonyl]-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester-->(1S,3S,6R)-N,N-dimethyl-7-oxabicyclo[4.1.0]heptane-3-carboxamide-->Dimethylamine hydrochloride | | Preparation Products | tert-butyl (1R,2S,5S)-2-aMino-5-(diMethylcarbaMoyl)cyclohexylcarbaMate |
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