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Propargyl-PEG7-NHS ester manufacturers
- Propargyl-PEG7-NHS
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2026-07-24
- CAS:2093152-77-1
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Propargyl-PEG7-NHS ester Basic information |
| Product Name: | Propargyl-PEG7-NHS ester | | Synonyms: | Propargyl-PEG7-NHS ester;Propargyl-PEG6-CH2CH2COONHS;4,7,10,13,16,19,22-Heptaoxapentacos-24-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester;2,5-Dioxopyrrolidin-1-yl 4,7,10,13,16,19,22-heptaoxapentacos-24-yn-1-oate;Propargyl-PEG6-C2-CONHS ester;Propargyl-PEG6-CH2CH2COONHS/4,7,10,13,16,19,22-Heptaoxapentacos-24-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester;Propyne heptapolyethylene glycol succinimide ester;Propargyl-PEG7-NHS | | CAS: | 2093152-77-1 | | MF: | C22H35NO11 | | MW: | 489.51 | | EINECS: | | | Product Categories: | | | Mol File: | 2093152-77-1.mol |  |
| | Propargyl-PEG7-NHS ester Chemical Properties |
| Boiling point | 562.7±60.0 °C(Predicted) | | density | 1.21±0.1 g/cm3(Predicted) |
| | Propargyl-PEG7-NHS ester Usage And Synthesis |
| Description | Propargyl-PEG7-NHS ester contains a propargyl group and an NHS ester. As an amine reactive reagent, this product can be used for derivatizing peptides, antibodies, amine coated surfaces etc. In the presence of copper catalyst, propargyl group reacts with azide to yield a stable triazole linkage. The PEG units help increase the hydrophilicity of the reagent. | | Uses | Propargyl-PEG7-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG7-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | Cleavable Linker; PEGs; Alkyl/ether | | References | [1] Earl F Albone, et al. Eribulin-based antibody-drug conjugates and methods of use. US20170252458A1. |
| | Propargyl-PEG7-NHS ester Preparation Products And Raw materials |
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