- TCID
-
- $52.00
-
2026-08-08
- CAS:30675-13-9
- Purity: 98.87%
- Supply Ability: 10g
- TCID
-
- $1.00
-
2019-12-26
- CAS:30675-13-9
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 200kg
|
| Product Name: | TCID | | Synonyms: | 4,5,6,7-TETRACHLOROINDAN-1,3-DIONE;4,5,6,7-TETRACHLOROINDANE-1,3-DIONE;4,5,6,7-Tetrachloro-1,3-indanedione;4,5,6,7-Tetrachloroindane-1,3-dione 95+%;4,5,6,7-tetrachloro-2,3-dihydro-1H-indene-1,3-dione;TCID;1H-Indene-1,3(2H)-dione, 4,5,6,7-tetrachloro-;4,5,6,7-Tetrachloroindane-1,3-dione
4,5,6,7-Tetrachloroindan-1,3-dione | | CAS: | 30675-13-9 | | MF: | C9H2Cl4O2 | | MW: | 283.92 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 30675-13-9.mol |  |
| Melting point | 218-220 | | Boiling point | 448.1±45.0 °C(Predicted) | | density | 1.782±0.06 g/cm3(Predicted) | | storage temp. | +2C to +8C | | solubility | Soluble in DMSO (up to 25 mg/ml), | | form | Orange solid | | pka | 8.62±0.20(Predicted) | | color | White | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. | | InChI | 1S/C9H2Cl4O2/c10-6-4-2(14)1-3(15)5(4)7(11)9(13)8(6)12/h1H2 | | InChIKey | IDLAOWFFKWRNHB-UHFFFAOYSA-N | | SMILES | O=C1CC(C2=C(Cl)C(Cl)=C(Cl)C(Cl)=C21)=O |
| Hazard Codes | Xi | | WGK Germany | WGK 3 | | Hazard Note | Irritant | | Storage Class | 11 - Combustible Solids |
| Description | TCID (30675-13-9) inhibits ubiquitin C-terminal hydrolase L3 (UCH-L3). IC50=0.6 μM, 125-fold selective over UCH-L1, IC50=75 μM. Cell permeable. | | Uses | TCID is a small molecule inhibitor of DNA polymerase λ. | | storage | Store at -20°C | | References | [1] KERRY ROUTENBERG LOVE. Mechanisms, biology and inhibitors of deubiquitinating enzymes[J]. Nature chemical biology, 2007, 3 11: 697-705. DOI:10.1038/nchembio.2007.43 [2] NAMDORI R. MTANGO. Essential role of ubiquitin C-terminal hydrolases UCHL1 and UCHL3 in mammalian oocyte maturation[J]. Journal of Cellular Physiology, 2011, 227 5: 2022-2029. DOI:10.1002/jcp.22931 |
| | TCID Preparation Products And Raw materials |
|