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| | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT Basic information |
| Product Name: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT | | Synonyms: | DLPS;1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT;12:0 PS (SODIUM SALT);1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (SODIUM SALT);12:0 PS;12:0 PS;Sodium (S)-2-amino-3-((((R)-2,3-bis(dodecanoyloxy)propoxy)oxidophosphoryl)oxy)propanoate;1,2-dilauroyl-sn-glycero-3-phospho-L-serine;Sodium (S)-2-amino-2-carboxyethyl ((R)-2,3-bis(dodecanoyloxy)propyl) phosphate | | CAS: | 208757-51-1 | | MF: | C30H59NNaO10P | | MW: | 647.76 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT Chemical Properties |
| storage temp. | -20°C | | form | powder | | InChIKey | QBSSGICBQYAHPS-OUPRKWGVSA-M | | SMILES | [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+] |
| Storage Class | 11 - Combustible Solids |
| | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT Usage And Synthesis |
| Description | DLPS, also known as 1,2-dilauroyl-sn-glycero-3-phospho-L-serine, is an anionic phospholipid with lauric acid tails (12:0) and contains a carboxylic acid (COOH) and amine (NH2) in their head group. It has been used in the preparation of lipid-mixing vesicles, liposome, or artificial membrane. Due to the medium size of fatty acid chain, DLPS is used to form thinner membranes/walls. | | Uses | 12:0 PS may be used:
- in the preparation of large unilamellar vesicles (LUVs)
- as a standard to spike replicas of extracted lipid dropletsand calibration curve generation for lipidomic analysis
- to study its effects on α-secretase activity
| | General Description | Phosphatidylserine (PS), an aminophospholipid is negatively charged and accounts for 2–10% of total cellular lipid. It is located in the membrane leaflets. | | Biochem/physiol Actions | Phosphatidylserine (PS) plays a key role in protein kinase C pathways. It also helps in confining the intracellular proteins to membrane leaflets of cytosol. |
| | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT Preparation Products And Raw materials |
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