- Azoxybenzene
-
-
2026-08-21
- CAS:495-48-7
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 30tons/month
- AZOXYBENZENE
-
- $1.00
-
2019-12-25
- CAS:495-48-7
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 1000KGS
|
| | AZOXYBENZENE Basic information |
| Product Name: | AZOXYBENZENE | | Synonyms: | (Z)-diphenyldiazene N-oxide;1,2-Diphenyldiazene 1-oxide;AZOXYBENZENE;Azobenzene, oxide;diphenyldiazene1-oxide;diphenyldiazine1-oxide;Fentoxan;Orde-naryazoxybenzene | | CAS: | 495-48-7 | | MF: | C12H10N2O | | MW: | 198.22 | | EINECS: | 207-802-1 | | Product Categories: | Pharmaceutical Intermediates | | Mol File: | 495-48-7.mol |  |
| | AZOXYBENZENE Chemical Properties |
| Melting point | 32-36 °C | | Boiling point | 130 °C / 0.9mmHg | | density | 1.16 | | refractive index | 1.6330 (estimate) | | storage temp. | 0-6°C | | color | Yellow, rhombic crystals | | Merck | 14,923 | | BRN | 743984 | | Dielectric constant | 5.1（40℃） | | Major Application | agriculture
environmental | | InChI | 1S/C12H10N2O/c15-14(12-9-5-2-6-10-12)13-11-7-3-1-4-8-11/h1-10H/b14-13- | | InChIKey | GAUZCKBSTZFWCT-YPKPFQOOSA-N | | SMILES | [O-]\[N+](=N/c1ccccc1)c2ccccc2 | | CAS DataBase Reference | 495-48-7(CAS DataBase Reference) | | EPA Substance Registry System | Azoxybenzene (495-48-7) |
| Hazard Codes | Xn | | Risk Statements | 20/22 | | Safety Statements | 28A-28 | | WGK Germany | 1 | | RTECS | CO4025000 | | TSCA | TSCA listed | | HS Code | 29153100 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Acute Tox. 4 Inhalation
Acute Tox. 4 Oral | | Hazardous Substances Data | 495-48-7(Hazardous Substances Data) | | Toxicity | LD50 orl-rat: 620 mg/kg AMIHBC 10,61,54 |
| | AZOXYBENZENE Usage And Synthesis |
| Description | Azoxybenzene is an obsolete insecticide used to control aphids and other sucking insects. It has a low aqueous solubility and is highly volatile. Little else is known about its environmental fate and behaviour. Ecotoxicology data is scant but it is moderately toxic to fish. Azoxybenzene is moderately toxic to mammals including humans if ingested. It may be a liver and kidney toxicant and is a recognised irritant. | | Chemical Properties | ORANGE-YELLOW TO ORANGE CRYSTALS | | Uses | Intermediate in organic synthesis. | | Uses | Fenazox is used in the synthetic preparation of amides via reductive amidation of esters, which is used in the synthesis of bio-active molecules and natural products. | | Definition | ChEBI: Azoxybenzene is an azoxy compound. | | Production Methods | Azoxybenzene is commercially produced through the partial reduction of nitrobenzene under alkaline conditions, typically using sodium hydroxide and a reducing agent such as glucose or sodium acetate. In one common method, nitrobenzene is heated with sodium hydroxide and glucose at 55–75 DegC, leading to the formation of azoxybenzene via intermediate steps involving phenylhydroxylamine and nitrosobenzene. The product is then isolated by steam distillation, followed by acidification and crystallisation. | | General Description | Bright yellow crystals or yellowish-brown solid. | | Air & Water Reactions | Dust may form an explosive mixture in air. Insoluble in water. | | Reactivity Profile | AZOXYBENZENE is an azo compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. | | Fire Hazard | Flash point data for AZOXYBENZENE are not available; however, AZOXYBENZENE is probably combustible. | | Mechanism of action | Non-systemic, contact action. | | Safety Profile | Poison by
subcutaneous route. Moderately toxic by
ingestion, skin contact, and other routes. A
skin and eye irritant. Mutation data reported.
Combustible. When heated to
decomposition it emits toxic fumes of NOx. | | Purification Methods | Crystallise azobenzene from EtOH or MeOH, and dry it for 4hours at 25o/10-3mm. Sublime it before use. [Bigelow & Palm Org Synth Coll Vol II 57 1943, Beilstein 16 II 326.] | | Pesticide Type | Insecticide; Acaricide |
| | AZOXYBENZENE Preparation Products And Raw materials |
|