DL-CAPROYLCARNITINE CHLORIDE manufacturers
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| | DL-CAPROYLCARNITINE CHLORIDE Basic information |
| Product Name: | DL-CAPROYLCARNITINE CHLORIDE | | Synonyms: | (+/-)-HEXANOYLCARNITINE CHLORIDE;DL-HEXANOYLCARNITINE CHLORIDE;DL-CAPROYLCARNITINE CHLORIDE;Zinc02517065;Hexanoyl-DL-carnitine chloride;Hexanoyl-L-carnitine HCl;3-carboxy-2-(hexanoyloxy)-N,N,N-trimethylpropan-1-aminium;DL-Hexanoylcarnitine chloride | | CAS: | 6920-35-0 | | MF: | C13H26ClNO4 | | MW: | 295.8 | | EINECS: | | | Product Categories: | Lipid signaling | | Mol File: | 6920-35-0.mol |  |
| | DL-CAPROYLCARNITINE CHLORIDE Chemical Properties |
| Melting point | 156-158°C | | storage temp. | −20°C | | solubility | Methanol (Slightly), Water (Slightly) | | form | Solid | | color | White to Off-White | | Water Solubility | Soluble to 100 mM in water | | Stability: | Hygroscopic | | InChI | 1S/C13H26NO4.ClH/c1-5-6-7-8-13(17)18-11(9-12(15)16)10-14(2,3)4;/h11H,5-10H2,1-4H3,(H,15,16);1H | | InChIKey | AWUOLOICNWRXPY-UHFFFAOYSA-N | | SMILES | Cl.CCCCCC(=O)OC(CC(O)=O)C[N](C)(C)C |
| Hazard Codes | Xn | | Risk Statements | 22-43 | | Safety Statements | 36/37 | | WGK Germany | 2 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Skin Sens. 1 |
| | DL-CAPROYLCARNITINE CHLORIDE Usage And Synthesis |
| Uses | (±)-Hexanoylcarnitine Chloride acts as a potential absorption-enhancing agents when used in drugs that are poorly absorbed, particularly in the gastrointestinal track. | | Biological Activity | (±)-hexanoylcarnitine chloride is an agonist for cholinergic and a homolog of acetylcarnitine chloride (cat no. b6273).acetylcholine receptor (achr) is an integral membrane protein receptor for acetylcholine. there are two kinds of achrs: nicotinic acetylcholine receptors and muscarinic acetylcholine receptors.(±)-hexanoylcarnitine chloride is a cholinergic agonist and an intermediate in lipid metabolism [1]. in retinal ganglion cells, acetylcarnitine and acetylcholine inhibited gabaergic responses to exogenous gaba and gabaergic inhibitory postsynaptic currents [2].in dogs with coronary ligation, (-)-carnitine chloride (lcc) (300 mg/kg) and acetyl (-)-carnitine chloride (alcc) (300 mg/kg) inhibited the ventricular arrhythmia. also, lcc and alcc improved oxidative phosphorylation rate and the mitochondrial function [1]. in the mouse hot plate test, acetyl-l-carnitine (alcar) (100 mg/kg) exhibited analgesia. while, u-73122 and neomycin (the phospholipase c (plc) inhibitors) blocked the increase of the pain threshold induced by alcar. licl that impairing phosphatidylinositol synthesis antagonized the antinociception in a dose-dependent way. pma and pdbu (pkc activators) blocked the increase of the pain threshold in a dose-dependent way. these results suggested that alcar analgesia required the participation of the plc-ip3 pathway [3]. |
| | DL-CAPROYLCARNITINE CHLORIDE Preparation Products And Raw materials |
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