- 4-Cyanophenol
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- $5.00
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2026-09-02
- CAS:767-00-0
- Min. Order: 1KG
- Purity: 99%
- 4-Cyanophenol
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-
2026-06-30
- CAS:767-00-0
- Min. Order: 1KG
- Purity: 99.0%
- Supply Ability: 10000KGS
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| | 4-Cyanophenol Basic information |
| | 4-Cyanophenol Chemical Properties |
| Melting point | 110-113 °C(lit.) | | Boiling point | 146 °C / 2mmHg | | density | 1.1871 (rough estimate) | | refractive index | 1.5800 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | methanol: 0.1 g/mL, clear | | form | Crystalline Powder | | pka | 7.97(at 25℃) | | color | Off-white to beige-gray | | Water Solubility | slightly soluble | | BRN | 386130 | | Henry's Law Constant | 1.4×104 mol/(m3Pa) at 25℃, Hilal et al. (2008) | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChI | 1S/C7H5NO/c8-5-6-1-3-7(9)4-2-6/h1-4,9H | | InChIKey | CVNOWLNNPYYEOH-UHFFFAOYSA-N | | SMILES | Oc1ccc(cc1)C#N | | CAS DataBase Reference | 767-00-0(CAS DataBase Reference) | | NIST Chemistry Reference | 4-Hydroxybenzoic acid nitrile(767-00-0) | | EPA Substance Registry System | Benzonitrile, 4-hydroxy- (767-00-0) |
| Hazard Codes | Xn,Xi | | Risk Statements | 22-36/37/38 | | Safety Statements | 26-36-45-24/25 | | WGK Germany | 3 | | RTECS | DI4375000 | | Hazard Note | Irritant | | TSCA | TSCA listed | | HS Code | 29269095 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 4-Cyanophenol Usage And Synthesis |
| Chemical Properties | white crystalline powder or chips. 4-Hydroxybenzonitrile [767-00-0], 4-cyanophenol, 1-cyano-4-hydroxybenzene, Mr 119.2, forms colorless crystals of mp 113℃. 4-Hydroxybenzonitrile is produced by reaction of 4-bromophenol with copper (I) cyanide, by ammoxidation of p-cresol, by reaction of 4-chlorobenzonitrile with sodium methoxide, or by the catalyzed gas phase reaction of ethyl 4-hydroxybenzoate with ammonia. The nitrile is used for the production of the herbicides 3,5-dibromo- and 3,5-diiodo-4- hydroxybenzonitrile (Bromoxynil, Ioxynil, May & Baker). | | Uses | Intermediates of Liquid Crystals | | Uses | 4-Cyanophenol is a precursor for the synthesis of a vasodilator, Levcromakalim. Bromination of 4-cyanophenol results in bromoxynil, a commercial herbicide. It can also be used as a component of deep eutectic solvent (DES) mixture. | | Preparation | 4-Cyanophenol is produced by reaction of 4-bromophenol with copper (I) cyanide, by ammoxidation of p-cresol, by reaction of 4-chlorobenzonitrile with sodium methoxide, or by the catalyzed gas phase reaction of ethyl 4-hydroxybenzoate with ammonia. | | Definition | ChEBI: 4-cyanophenol is a member of phenols. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor. It is functionally related to a benzonitrile. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 39, p. 3343, 1974 DOI: 10.1021/jo00937a007 | | Purification Methods | Crystallise the phenol from pet ether, *benzene or water and keep it under vacuum over P2O5. [Bernasconi & Paschelis J Am Chem Soc 108 2969 1986.] [Beilstein 10 H 167, 10 IV 441.] |
| | 4-Cyanophenol Preparation Products And Raw materials |
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