Allopurinol riboside manufacturers
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| | Allopurinol riboside Basic information |
| Product Name: | Allopurinol riboside | | Synonyms: | 1-BETA-D-RIBOFURANOSYL-1H-PYRAZOLO[3,4-D]PYRIMIDINE-4-ONE;1-BETA-D-RIBOFURANOSYLPYRAZOLO[3,4-D]PYRIMIDIN-4-ONE;8-AZA-7-DEAZAINOSINE;1-β-d-ribofuranosyl-1h-pyrazolo[3,4-d]pyrimidine-4-one;1-[(2S,3S,4R,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]-2H-pyrazolo[4,5-e]pyrimidin-4-one;1,5-Dihydro-1-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one;Allopurinol ribonucleoside;Allopurinol-1-ribonucleoside | | CAS: | 16220-07-8 | | MF: | C10H12N4O5 | | MW: | 268.23 | | EINECS: | | | Product Categories: | | | Mol File: | 16220-07-8.mol |  |
| | Allopurinol riboside Chemical Properties |
| Boiling point | 715.0±60.0 °C(Predicted) | | density | 2.08±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO:5.0(Max Conc. mg/mL);18.64(Max Conc. mM)
PBS (pH 7.2):5.0(Max Conc. mg/mL);18.64(Max Conc. mM) | | form | A solid | | pka | 8.65±0.10(Predicted) | | color | White to off-white |
| | Allopurinol riboside Usage And Synthesis |
| Uses | Allopurinol riboside is a structural isomer of hypoxanthine. | | Definition | ChEBI: A nucleoside analogue that is allopurinol with a beta-D-ribofuranosyl moiety at the 1-position. | | in vivo | Allopurinol riboside peaks in plasma 1.6 hours after administration, has an elimination half-life of 3 hours, and steady-state concentrations in the therapeutic range[3]. After oral administration, unexpectedly low levels of allopurinol riboside in plasma are attributable to incomplete absorption and rapid renal clearance. Probenecid reduces the renal clearance of allopurinol riboside, extends the half-life of allopurinol riboside in plasma, and triples the levels of allopurinol riboside in plasma[4]. | | IC 50 | Leishmania |
| | Allopurinol riboside Preparation Products And Raw materials |
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