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Succinic anhydride

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  • Succinic anhydride
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  • $2.00
  • 2026-11-06
  • CAS:108-30-5
  • Min. Order: 1kg
  • Purity: 99.9% min
  • Supply Ability: 5000mt
  • Succinic anhydride
  • Succinic anhydride pictures
  • 2026-11-06
  • CAS:108-30-5
  • Min. Order: 1KG
  • Purity: 98%min
  • Supply Ability: 30tons/month
  • Succinic anhydride
  • Succinic anhydride pictures
  • $1.00
  • 2026-11-06
  • CAS:108-30-5
  • Min. Order: 1kg
  • Purity: ≥99%
  • Supply Ability: 2000mt/year

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Succinic anhydride Basic information
Product Name:Succinic anhydride
Synonyms:2,5(3H,4H)-Furandione;bernsteinsaureanhydrid;Bernsteinsaure-anhydrid;dihydro-5-furandione;Dihydro-furan-2,5-dione;NCI-C55696;Oxolan-2,5-dione;rikacidsa
CAS:108-30-5
MF:C4H4O3
MW:100.07
EINECS:203-570-0
Product Categories:Building Blocks;Carbonyl Compounds;Carboxylic Acid Anhydrides;Chemical Synthesis;Organic Building Blocks;Heterocycles;Isotope Labelled Compounds;SuccinicSeries;Fine chemicals;bc0001;108-30-5
Mol File:108-30-5.mol
Succinic anhydride Structure
Succinic anhydride Chemical Properties
Melting point 118-120 °C (lit.)
Boiling point 261 °C (lit.)
density 1,572 g/cm3
bulk density550-600kg/m3
vapor density 3.5 (vs air)
vapor pressure 1 mm Hg ( 92 °C)
refractive index 1.4688 (estimate)
Fp 157°C
storage temp. Store below +30°C.
solubility 62.9g/l Hydrolysis
form Solid
pka4.67[at 20 ℃]
color White to Off-White
Specific Gravity1.2340 (20℃)
OdorOdorless
PH2.7 (10g/l, H2O)
Water Solubility <0.1 g/100 mL at 21 ºC (decomposes)
Sensitive Moisture Sensitive
Merck 14,8870
BRN 108441
Stability:Stable. Incompatible with oxidising agents, strong acids, strong bases, alcohols, amines. Avoid exposure to water or moisture.
InChI1S/C4H4O3/c5-3-1-2-4(6)7-3/h1-2H2
InChIKeyRINCXYDBBGOEEQ-UHFFFAOYSA-N
SMILESO=C1CCC(=O)O1
LogP2.44 at 40℃
CAS DataBase Reference108-30-5(CAS DataBase Reference)
NIST Chemistry Reference2,5-Furandione, dihydro-(108-30-5)
IARC3 (Vol. 15, Sup 7) 1987
EPA Substance Registry SystemSuccinic anhydride (108-30-5)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37-22
Safety Statements 25-46
RIDADR UN 3261 8 / PGII
WGK Germany 1
RTECS WN0875000
F 21
Autoignition Temperature480 °C
TSCA TSCA listed
HazardClass 8
HS Code 29171990
Storage Class8A - Combustible corrosive hazardous materials
Hazard ClassificationsAcute Tox. 4 Oral
Eye Dam. 1
Resp. Sens. 1
Skin Corr. 1B
Skin Sens. 1
Hazardous Substances Data108-30-5(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 1510 mg/kg
MSDS Information
ProviderLanguage
Butanedioic anhydride English
SigmaAldrich English
ACROS English
ALFA English
Succinic anhydride Usage And Synthesis
DescriptionSuccinic anhydride, also called di hydro - 2,5- furandione , is an organic compound with the molecular formula C4H4O3.This colorless solid is the acid anhydride of succinic acid.
Chemical PropertiesSuccinic anhydride is an odourless, colourless needle-like or white crystalline solid natural product. Molecular formula C4H4O3, molecular weight 100.07 g/mol, relative density 1.503, melting point 237 °F. 239 °F at 5 mmHg, 239 °F at 198 °F and 1 mmHg. Soluble in chloroform, carbon tetrachloride, and ethanol; very slightly soluble in ether and water (insoluble in water). Moderately toxic and irritating, emits pungent and irritating fumes when heated to decomposition.
Chemical Propertiesfine white crystalline solid
UsesIt was used in the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.It was also used in preparing functionalized oxide surfaces on a chip.
UsesSuccinic Anhydride is an acidulant that hydrolyzes very slowly to succinic acid in water. it has thermal stability and a low melting point of 118°c which permits it to be used in products at compara- tively low temperatures. it is used as a leavening acidulant for bak- ing powder.
UsesSuccinic Anhydride is a useful compound in the paper manufacturing process.
ApplicationAlkyl succinic anhydride (ASA) is used as a sizing agent or wet strength additive in paper production.
Production MethodsThe compound is produced from succinic anhydride and hydrogen peroxide . This material must be stabilized by using a dehydrating agent such as disodium sulfate or magnesium sulfate.
PreparationA solution of succinic acid (500 mg, 42 mmol) and triethylamine (1.23 mL, 42 mmol) in anhydrous THF (120 mL) was allowed to react with triphosgene (42 mg, 7.0 mmol) at ice-water temperature for 10 min. The reaction mixture was subsequently stirred for a further 15 min at room temperature. The solution was then filtered, and the filtrate was concentrated to dryness. The residue was crystallized from ethyl acetate to afford the desired product as white crystals (370 mg, 85%).
DefinitionChEBI: Succinic anhydride is a cyclic dicarboxylic anhydride and a tetrahydrofurandione. It is functionally related to a succinic acid.
Synthesis Reference(s)Synthetic Communications, 23, p. 419, 1993 DOI: 10.1080/00397919308009796
General DescriptionSuccinic anhydride is a cyclic anhydride of succinic acid with a five-membered ring. It is widely used in the manufacture of polymeric materials, pharmaceuticals, agrochemicals, dyes, surface-active agents, and organic flame-retardant materials. It also finds application as a cross-linking agent in ion-exchange membranes and a curing agent for epoxy resins.
General DescriptionColorless needles or white crystalline solid. Melting point 237°F. Sublimes at 239°F at 5 mm Hg pressure; and at 198°F and 1 mm Hg pressure. Moderately toxic and an irritant.
Air & Water ReactionsReacts slowly with water. Insoluble in water.
Reactivity ProfileSuccinic anhydride reacts exothermically with water. Reactions are usually slow, but might become violent if local heating accelerates their rate. Acids accelerate the reaction with water. Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases.
Fire HazardFlash point data for Succinic anhydride are not available, however, Succinic anhydride is probably combustible.
Flammability and ExplosibilityNot classified
Materials UsesSuccinic anhydride can be used:
(1) In the preparation of covalently cross-linked oxidized-alginate/N-succinyl-chitosan hydrogels, as injectable systems towards tissue engineering.
(2) In preparing functionalized oxide surfaces on a chip.
(3) As a starting material to synthesize polyesters in presence of a metal triflate as a catalyst.
(4) As a cross-linking agent to enhance the mechanicalproperties and antimicrobial activities of zein films.
Safety ProfileExperimental teratogenic effects. Moderately toxic by ingestion. A severe eye irritant. Mutation data reported. Questionable carcinogen with experimental neoplastigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also ANHYDRIDES.
Purification MethodsCrystallise the anhydride from redistilled acetic anhydride or CHCl3, then filter, wash with diethyl ether and dry it in a vacuum. [Beilstein 17 H 606, 17 V 6.]
Tag:Succinic anhydride(108-30-5) Related Product Information
2,3-Butanedione Dimethylglyoxime Trifluoromethanesulfonic anhydride Caronic anhydride Glutaric anhydride Chromium(VI) oxide Disodium succinate Polysebacic acid anhydride Succinimide Succinic acid Diphenylphosphoryl azide Maleic anhydride Phthalic anhydride 1,4-Diaminobutane Acetic anhydride Dodecenylsuccinic anhydride cis-1,2,3,6-Tetrahydrophthalic anhydride Itaconic anhydride