- Boc-Cyclolencine
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- $1.10
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2026-07-02
- CAS:35264-09-6
- Min. Order: 1KG
- Purity: 99%min
- Supply Ability: 100KG
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| | 1-N-Boc-Aminocyclopentanecarboxylic acid Basic information |
| Product Name: | 1-N-Boc-Aminocyclopentanecarboxylic acid | | Synonyms: | 1-TERT-BUTYLOXYCARBONYLAMINO-CYCLOPENTANE-1-CARBOXYLIC ACID;Boc-1-aminocyclopentane-1-carboxy acid;1-N-BOC-Aminocyclopentanecarboxylic acid,98%;Boc-Cyclolencine;Boc-cycloleucine Boc-1-aMinocyclopentane-1-carboxy acid;1-N-BOC-AMinocyclopentanecarboxylic acid, 98% 1GR;1-(Boc-amino)cyclopentanecarboxylic Acid
N-Boc-cycloleucine;BOC-1-AMINO-1-CYCLOPENTANECARBOXYLIC ACID | | CAS: | 35264-09-6 | | MF: | C11H19NO4 | | MW: | 229.27 | | EINECS: | 000-000-0 | | Product Categories: | pharmacetical | | Mol File: | 35264-09-6.mol |  |
| | 1-N-Boc-Aminocyclopentanecarboxylic acid Chemical Properties |
| Melting point | 130-135 °C | | Boiling point | 376.6±21.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | pka | 4.14±0.20(Predicted) | | form | Crystalline Powder | | color | White to off-white | | Water Solubility | Soluble in hot water | | BRN | 2734412 | | CAS DataBase Reference | 35264-09-6(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29242990 |
| | 1-N-Boc-Aminocyclopentanecarboxylic acid Usage And Synthesis |
| Chemical Properties | white to off-white crystalline powder | | Uses | Boc-Cycloleucine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | | Synthesis | Cycloleucine (1.0 g, 7.74 mmol), triethylamine (Et3N, 5.4 mL, 38.7 mmol), 1 M aqueous NaOH (7.74 mL, 7.74 mmol) and acetonitrile (CH3CN, 10 mL) were added to a 250 mL round-bottom flask. The resulting clarified solution was cooled to 0 °C, followed by the slow addition of di-tert-butyl dicarbonate ((Boc)2O). The reaction mixture was gradually warmed to room temperature and stirred continuously for 4 h. A white precipitate was generated during the reaction. After completion of the reaction, the mixture was concentrated and the residue was dissolved in a solvent mixture of ethyl acetate (EtOAc) and water (1:1, 100 mL). The organic phase was separated and the aqueous phase was acidified with 10% HCl and then extracted three times with EtOAc. All organic phases were combined, washed with water and saturated saline in turn, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated to give 1-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid as a white solid (1.29 g, 73% yield). | | References | [1] Chemistry - A European Journal, 2011, vol. 17, # 19, p. 5256 - 5260
[2] Tetrahedron Letters, 1996, vol. 37, # 20, p. 3441 - 3444
[3] Organic Process Research and Development, 1998, vol. 2, # 4, p. 238 - 244
[4] Patent: WO2004/22534, 2004, A1. Location in patent: Page 39
[5] Patent: WO2017/21922, 2017, A1. Location in patent: Page/Page column 29 |
| | 1-N-Boc-Aminocyclopentanecarboxylic acid Preparation Products And Raw materials |
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