SHMT-IN-1 manufacturers
- SHMT-IN-1
-
- $48.00
-
2026-08-26
- CAS:1508286-18-7
- Purity: 99.80%
- Supply Ability: 10g
- SHMT-IN-1
-
- $48.00
-
2026-08-26
- CAS:1508286-18-7
- Purity: 99.80%
- Supply Ability: 10g
|
| | SHMT-IN-1 Basic information |
| Product Name: | SHMT-IN-1 | | Synonyms: | SHMT-IN-1;SHMT IN 1,SHMTIN1;Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-cyclobutyl-4-(3,5-dichlorophenyl)-1,4-dihydro-3-methyl-;6-Amino-4-cyclobutyl-4-(3,5-dichlorophenyl)-1,4-dihydro-3-methylpyrano[2,3-c]pyrazole-5-carbonitrile;SHMT-IN-1, 10 mM in DMSO | | CAS: | 1508286-18-7 | | MF: | C18H16Cl2N4O | | MW: | 375.25 | | EINECS: | | | Product Categories: | | | Mol File: | 1508286-18-7.mol |  |
| | SHMT-IN-1 Chemical Properties |
| Boiling point | 634.6±55.0 °C(Predicted) | | density | 1.49±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 250 mg/mL (666.22 mM; Need ultrasonic) | | pka | 11.46±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | SHMT-IN-1 Usage And Synthesis |
| Uses | SHMT-IN-1 (compound (±)-46) is a potent inhibitor of plasmodial serine hydroxymethyltransferase (SHMT). SHMT-IN-1 has antitumor activity[1]. | | Biological Activity | SHMT-IN-1 (compound (±)-46) is a potent inhibitor of plasmodial serine hydroxymethyltransferase (SHMT). SHMT-IN-1 has antitumor activity[1]. | | References | [1]. Witschel MC, et al. Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities. J Med Chem. 2015 Apr 9;58(7):3117-30. |
| | SHMT-IN-1 Preparation Products And Raw materials |
|