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| | (S,S)-Formoterol Basic information |
| Product Name: | (S,S)-Formoterol | | Synonyms: | (S,S)-Formoterol;Formamide, N-[2-hydroxy-5-[(1S)-1-hydroxy-2-[[(1S)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-;Formamide, N-[2-hydroxy-5-[1-hydroxy-2-[[2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, [S-(R*,R*)]-;N-[2-Hydroxy-5-[(1S)-1-hydroxy-2-[[(αS)-α-methyl-4-methoxyphenethyl]amino]ethyl]phenyl]formamide;N-[2-Hydroxy-5-[(S)-1-hydroxy-2-[[(S)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]formamide;Formoterol Impurity 15;N-(2-hydroxy-5-((S)-1-hydroxy-2-(((S)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide;2-amino-1-(3-amino-4-(benzyloxy)phenyl)ethan-1-ol | | CAS: | 67346-48-9 | | MF: | C19H24N2O4 | | MW: | 344.4 | | EINECS: | | | Product Categories: | | | Mol File: | 67346-48-9.mol |  |
| | (S,S)-Formoterol Chemical Properties |
| Boiling point | 603.2±55.0 °C(Predicted) | | density | 1.233±0.06 g/cm3(Predicted) | | pka | 8.95±0.50(Predicted) |
| | (S,S)-Formoterol Usage And Synthesis |
| Uses | (S,S)-Formoterol ((+)-Formoterol) is a (S,S)-enantiomer of Formoterol. (S,S)-Formoterol can promote asthma by enhancing IL-4 production in mast cells of the asthmatic airway[1]. | | Definition | ChEBI: (S,S)-formoterol is an N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide in which both of the stereocentres have S configuration. It is a conjugate base of a (S,S)-formoterol(1+). It is an enantiomer of an arformoterol. | | References | [1] Abraha D, et, al. (S,S)-formoterol increases the production of IL-4 in mast cells and the airways of a murine asthma model. Int Arch Allergy Immunol. 2004 Apr;133(4):380-8. DOI:10.1159/000077358
[2] Jensen O, et, al. Stereoselective cell uptake of adrenergic agonists and antagonists by organic cation transporters. Biochem Pharmacol. 2020 Jan;171:113731. DOI:10.1016/j.bcp.2019.113731 |
| | (S,S)-Formoterol Preparation Products And Raw materials |
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