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| | 7-Ethyl-10-hydroxycamptothecin,98% Basic information |
| Product Name: | 7-Ethyl-10-hydroxycamptothecin,98% | | Synonyms: | (S)-4,7-Diethyl-4,10-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-3,14(4H,12H)-dione;4,7-Diethyl-10-hydroxycamptothecin;1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,7-diethyl-4,10-dihydroxy-, (S)- (9CI);(S)?-4,?7-Diethyl-?4,?10-?dihydroxy-1H-?pyrano[3',?4':6,?7]?indolizino[1,?2-?b]?quinoline-?3,?14(4H,?12H)?-?dione;Camptothecin Impurity 7;12-Ethyl-9-hydroxycamptothecin;7-Ethyl-10-hydroxycamptothecin 119577-28-5 For Human Health;(S)-4,7-Diethyl-4,10-dihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione | | CAS: | 119577-28-5 | | MF: | C22H20N2O5 | | MW: | 392.4 | | EINECS: | | | Product Categories: | | | Mol File: | 119577-28-5.mol |  |
| | 7-Ethyl-10-hydroxycamptothecin,98% Chemical Properties |
| Boiling point | 813.7±65.0 °C(Predicted) | | density | 1.51±0.1 g/cm3(Predicted) | | pka | 9.08±0.40(Predicted) | | form | Solid | | color | White to off-white |
| | 7-Ethyl-10-hydroxycamptothecin,98% Usage And Synthesis |
| Chemical Properties | Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the fruit of Camptotheca acuminata. | | Uses | 12-Ethyl-9-hydroxycamptothecin is a derivative of Camptothecin. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM[1]. | | References | [1] Luzzio MJ, et al. Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I. J Med Chem. 1995;38(3):395-401. DOI:10.1021/jm00003a001 |
| | 7-Ethyl-10-hydroxycamptothecin,98% Preparation Products And Raw materials |
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