- 1-Bromoethyl acetate
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- $0.00 / 1kg
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2026-04-29
- CAS:40258-78-4
- Min. Order: 1kg
- Purity: 97%
- Supply Ability: 1000kg
- 1-Bromoethyl acetate
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- $0.00 / 1kg Ton
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2026-04-09
- CAS:40258-78-4
- Min. Order: 1kg Ton
- Purity: 98%+
- Supply Ability: 2 tons/month
- 1-Bromoethyl acetate
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- $0.00 / 25kg
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2025-12-01
- CAS:40258-78-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10000KGS
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| | 1-Bromoethyl acetate Basic information |
| Product Name: | 1-Bromoethyl acetate | | Synonyms: | 1-ACETOXY ETHYL BROMIDE;1-BROMOETHYLACETATE;1-Bromoethyl acetate ,90%;(RS)-1-Acetoxyethyl BroMide;1 - broMine ethyl acetate;1-Bromoethyl acetate[BEA];Cefuroxime Impurity 51;1-Acetoxy Ethyl Bromide (1-AEB) CAS No. : 40258-78-4 | | CAS: | 40258-78-4 | | MF: | C4H7BrO2 | | MW: | 167 | | EINECS: | 609-807-8 | | Product Categories: | | | Mol File: | 40258-78-4.mol |  |
| | 1-Bromoethyl acetate Chemical Properties |
| Boiling point | 122-125 °C(Press: 738 Torr) | | density | 1.48 | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Chloroform (Sparingly), Methanol (Sparingly) | | form | Oil | | color | Colourless to Dark Brown | | Stability: | Hygroscopic | | InChI | InChI=1S/C4H7BrO2/c1-3(5)7-4(2)6/h3H,1-2H3 | | InChIKey | IIASCQBFNHWZBE-UHFFFAOYSA-N | | SMILES | C(OC(=O)C)(Br)C |
| Safety Statements | 24/25 | | HS Code | 29153900 |
| | 1-Bromoethyl acetate Usage And Synthesis |
| Chemical Properties | Pale Yellow Oil | | Uses | 1-Bromoethyl Acetate is a 1-haloalkyl ester that is used in the modification of of antibiotics. It is an intermediate that can be usefully used in the preparation of the oral antibiotic Cefuroxime axetil. | | Synthesis | 1-bromoethyl acetate is prepared by reacting acetyl bromide and acetaldehyde using zinc chloride as a catalyst.
After cooling 30 ml of hydrogen bromide / acetic acid (1.2 equiv) to 0 ° C., 53.5 ml (1.0 equiv) of vinyl acetate was slowly added thereto, followed by stirring for 1 hour. It was extracted with dichloromethane, washed with distilled water at 0-5 ° C., dehydrated with anhydrous magnesium sulfate, and distilled under reduced pressure to obtain 81.4 g of 1-bromoethyl acetate.
 | | References | [1] Patent: CN108383727, 2018, A. Location in patent: Paragraph 0052-0053; 0056-0057; 0061-0062; 0065-0074
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 16, p. 5915 - 5926 |
| | 1-Bromoethyl acetate Preparation Products And Raw materials |
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