| Company Name: |
Energy Chemical |
| Tel: |
400-0056266 |
| Email: |
sales8178@energy-chemical.com |
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| | 5-Chloro-2-formylpyridine Basic information |
| | 5-Chloro-2-formylpyridine Chemical Properties |
| Melting point | 66-68° | | Boiling point | 208℃ | | density | 1.332 | | Fp | 79℃ | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | form | powder to crystal | | pka | 1.44±0.10(Predicted) | | color | White to Yellow to Orange | | InChI | InChI=1S/C6H4ClNO/c7-5-1-2-6(4-9)8-3-5/h1-4H | | InChIKey | YYLBDBOSXXSZQQ-UHFFFAOYSA-N | | SMILES | C1(C=O)=NC=C(Cl)C=C1 |
| Hazard Codes | Xi | | Risk Statements | 36-43 | | Safety Statements | 26-36/37 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 2933399990 | | Storage Class | 11 - Combustible Solids |
| | 5-Chloro-2-formylpyridine Usage And Synthesis |
| Synthesis | Ethyl 5-chloropyridine-2-carboxylate (146 mg, 76% yield) was obtained by reacting 5-chloropyridine-2-carboxylic acid (200 mg, 1.03 mmol) in ethanol (3 mL) and a dioxane solution (0.5 mL) of 4M HCl at 90 °C for 20 hours. Subsequently, ethyl 5-chloropyridine-2-carboxylate (146 mg, 0.786 mmol) was dissolved in dichloromethane (4.0 mL), to which a toluene solution of 1M DIBAL (1.74 mL, 1.74 mmol) was added and reacted for 20 min to give 5-chloropyridine-2-carbaldehyde (58 mg, 52% yield). The product was analyzed by GC-MS and the molecular ion peak (M+) was 141. | | References | [1] Patent: WO2004/14902, 2004, A2. Location in patent: Page 42 |
| | 5-Chloro-2-formylpyridine Preparation Products And Raw materials |
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