2-Amino-5-ethylpyrazine manufacturers
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| | 2-Amino-5-ethylpyrazine Basic information |
| | 2-Amino-5-ethylpyrazine Chemical Properties |
| Boiling point | 250.2±35.0 °C(Predicted) | | density | 1.109±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 3.50±0.10(Predicted) |
| | 2-Amino-5-ethylpyrazine Usage And Synthesis |
| Synthesis | Step 1: Hydrogenation reaction. 5-Ethynyl-2-aminopyrazine (18 mg, 0.151 mmol) was dissolved in ethyl acetate (500 μL) under stirring conditions and triethylamine (63 μL, 0.45 mmol) and Pd(OH)2/carbon catalyst (0.01 mmol, 20% wt on carbon) were added sequentially. The reaction system was placed in a hydrogen atmosphere at 45 psi and the reaction was shaken for 6 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford the off-white solid product 2-amino-5-ethylpyrazine in 84% yield. | | References | [1] Patent: US2003/69284, 2003, A1 |
| | 2-Amino-5-ethylpyrazine Preparation Products And Raw materials |
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